Generic Name: Cortisone Brand Name(s): Cortisone.

Uses

What is Cortisone used for?

Cortisone is commonly used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, and certain cancers.

How should I take Cortisone?

Take this medication by mouth with food or milk to prevent stomach upset. Take this medication by mouth with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. If you take this medication once daily, take it in the morning before 9 AM. If you are taking this medication every other day or on another schedule besides a daily one, it may help to mark your calendar with a reminder.

The dosage and length of treatment are based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. It is important to continue taking this medication even if you feel well. Follow the dosing schedule carefully, and take this medication exactly as prescribed.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Inform your doctor if your condition persists or worsens.

How do I store Cortisone?

Cortisone is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Cortisone in the bathroom or the freezer. There may be different brands of Cortisone that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Cortisone down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Cortisone?

Before taking cortisone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: untreated active fungal infections.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, history of blood clots, brittle bones (osteoporosis), diabetes, eye diseases (e.g., cataracts, glaucoma, herpes infection of the eye), heart problems (e.g., congestive heart failure), high blood pressure, other infections (e.g., tuberculosis, herpes), kidney disease, liver problems (e.g., cirrhosis), mental/mood conditions (e.g., psychosis, anxiety, depression), low blood minerals (e.g., low potassium or calcium), stomach/intestinal problems (e.g., ulcer, ulcerative colitis, diverticulitis), thyroid problems.

This medication may mask signs of infection or put you at greater risk of developing very serious infections. Report any injuries or signs of infection (e.g., persistent sore throat/fever/cough, pain during urination, muscle aches) that occur during treatment.

Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication.

Do not have immunizations, vaccinations or skin tests unless specifically directed by your doctor. Live vaccines may cause serious complications (e.g., infection) if given while you are taking this medication. Avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.

Avoid contact with people who have chickenpox or measles unless you have previously had these diseases (e.g., in childhood). If you are exposed to one of these infections and you have not previously had it, seek immediate medical attention.

If you have a history of ulcers or take large doses of aspirin or other arthritis medication, limit alcoholic beverages while taking this medication to decrease the risk of stomach/intestinal bleeding.

If you have diabetes, this drug may make it harder to control your blood sugar levels. Monitor your blood sugar levels regularly and inform your doctor of the results. Your medicine, exercise plan, or diet may need to be adjusted.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication may slow down a child’s growth if used for a long time. Consult the doctor or pharmacist for more details. See the doctor regularly so your child’s height and growth can be checked.

This medication should be used only when clearly needed during pregnancy. There have been rare reports of harm to the unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for an extended time may have low levels of corticosteroid hormone. Tell your doctor right away if you notice symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Cortisone during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this Cortisone. This Cortisone is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Cortisone?

Stomach upset, headache, dizziness, menstrual changes (e.g., delayed/irregular/absent periods), trouble sleeping, increased appetite, or weight gain may occur.

If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: black stools, bone/joint pain, easy bruising/bleeding, fast/pounding/irregular heartbeat, increased thirst/urination, mental/mood changes (e.g., depression, mood swings, agitation), muscle pain, persistent weight gain, puffy face, slow wound healing, seizures, signs of infection (e.g., fever, persistent sore throat), stomach/abdominal pain, swelling of the ankles/feet, thinning skin, trouble breathing, unusual hair growth, unusual skin growths, vision changes, vomit that looks like coffee grounds, weakness.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Cortisone?

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: aldesleukin, birth control pills, diabetes medications, estrogen hormone replacement, mifepristone, drugs affecting liver enzymes that remove cortisone from your body (such as azole antifungals including ketoconazole, barbiturates including phenobarbital, rifamycins including rifampin, certain anti-seizure medications including phenytoin), drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, “blood thinners” such as dabigatran/warfarin, NSAIDs such as aspirin/celecoxib/ibuprofen).

If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

This medication may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Cortisone may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Cortisone?

Cortisone may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Cortisone?

Cortisone may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Cortisone.

What is the dose of Cortisone for an adult?

Usual Adult Dose for Adrenal Insufficiency

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Idiopathic (Immune) Thrombocytopenic Purpura

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Shock

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Hemolytic Anemia

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Erythroblastopenia

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Loeffler’s Syndrome

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Sarcoidosis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Berylliosis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Lymphoma

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Nephrotic Syndrome

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Uveitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Iritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Keratitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Conjunctivitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Iridocyclitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Chorioretinitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Choroiditis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Systemic Lupus Erythematosus

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Dermatomyositis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Ankylosing Spondylitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Bursitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Osteoarthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Rheumatoid Arthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Gouty Arthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Psoriatic Arthritis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Usual Adult Dose for Epicondylitis

25 mg to 300 mg per day, oral or IM, in 1 to 2 divided doses.

Renal Dose Adjustments

Steroids should be used with caution in patients with renal insufficiency.

Liver Dose Adjustments

Steroids should be used with caution in patients with cirrhosis.

Dose Adjustments

Dosages smaller than 25 mg per day may be enough in less severe diseases. In severe diseases dosages higher than 300 mg per day may be required.

Maintain patient on lowest dosage that provides an adequate clinical response, by decreasing the initial dosage gradually in small amounts.

Titrate patient off therapy gradually if drug has been used for a few days.

Precautions

Secondary adrenocortical insufficiency may result from rapid withdrawal of cortisone and may be minimized with gradual tapering of dosage.

Dialysis

Supplemental dose is not necessary.

Other Comments

The injectable suspension is intended for intramuscular administration only.

What is the dose of Cortisone for a child?

Usual Pediatric Dose for Adrenal Insufficiency

0.5 mg to 0.75 mg/kg/day orally given in equally divided doses every 8 hours. Alternatively, 0.25 mg to 0.35 mg/kg IM once daily

How is Cortisone available?

Cortisone is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Cortisone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 18, 2018 | Last Modified: January 18, 2018

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