Generic Name: Cloxacillin Brand Name(s): Generics only. No brands available.

Know the basics

What is cloxacillin used for?

Cloxacillin is used to treat a wide variety of bacterial infections. Cloxacillin is a type of penicillin antibiotic. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. Cloxacillin will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

How should I take cloxacillin?

Take cloxacillin by mouth as directed by your doctor. Cloxacillin is best absorbed when taken on an empty stomach (1 hour before or 2 hours after meals).

If you are using the liquid suspension form of cloxacillin , shake the bottle well before each dose.

The dosage is based on your medical condition and response to therapy. In children, the dosage is also based on weight and age.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.

Continue to take cloxacillin until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.

Inform your doctor if your condition persists or worsens.

How do I store cloxacillin?

Cloxacillin is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store cloxacillin in the bathroom or the freezer. There may be different brands of cloxacillin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush cloxacillin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using cloxacillin?

Take all of the cloxacillin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Do not break, chew, open, or crush the capsules. Swallow them whole.

Cloxacillin may decrease the effectiveness of birth control pills. Use a second method of birth control while taking cloxacillin to protect against pregnancy.

Is it safe to take cloxacillin during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown.

Know the side effects

What are the side effects of cloxacillin?

If you experience any of the following serious side effects, stop taking cloxacillin and seek emergency medical attention:

  • an allergic reaction (shortness of breath; closing of your throat; hives; swelling of your lips, face, or tongue; rash; or fainting);
  • seizures;
  • severe watery diarrhea and abdominal cramps; or
  • unusual bleeding or bruising.

Other, less serious side effects maybe more likely to occur. Continue to take cloxacillin and talk to your doctor if you experience

  • mild nausea, vomiting, diarrhea, or abdominal pain;
  • white patches on the tongue (thrush/yeast infection);
  • itching or discharge of the vagina (vaginal yeast infection); or
  • black, “hairy” tongue or sore mouth or tongue.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with cloxacillin?

Cloxacillin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, non-prescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some drugs may decrease the effects of cloxacillin and prevent it from properly treating your infection. Before taking cloxacillin, tell your doctor if you are taking any of the following drugs:

  • cholestyramine (Questran) or colestipol (Colestid);
  • another antibiotic (for the same or for a different infection) such as erythromycin (Ery-Tab, E-Mycin, E.E.S., others), tetracycline (Sumycin, others), minocycline (Minocin), doxycycline (Doryx, Vibramycin, others), or any other.

Does food or alcohol interact with cloxacillin?

Cloxacillin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with cloxacillin?

Cloxacillin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Understand the Dosage

The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before using this medication.

What is the dose of Cloxacillin for an adult?

Usual Adult Dose for Upper Respiratory Tract Infection:

250 mg orally every 6 hours for 7 to 14 days, depending on the nature and severity of the infection.

Maximum dose: 4 g/day.

Usual Adult Dose for Pneumonia:

500 mg orally every 6 hours for up to 21 days, depending on the nature and severity of the infection.

Maximum dose: 4 g/day.

Usual Adult Dose for Skin and Structure Infection:

500 mg orally every 6 hours for 7 days, or until 3 days after acute inflammation resolves, depending on the nature and severity of the infection.

Maximum dose: 4 g/day.

Usual Adult Dose for Cystitis:

250 mg orally every 6 hours for 3 to 7 days, depending on the nature and severity of the infection. Cloxacillin is rarely indicated for the treatment of cystitis.

Maximum dose: 4 g/day.

What is the dose of Cloxacillin for a child?

Usual Pediatric Dose for Pneumonia:

The dosage has not been established in pediatric patients less than 1 year old. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

1 year to 18 years: 50 to 100 mg/kg/day orally divided every 6 hours.

Maximum dose: 4 g/day.

Usual Pediatric Dose for Upper Respiratory Tract Infection:

The dosage has not been established in pediatric patients less than 1 year old. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

1 year to 18 years: 50 to 100 mg/kg/day orally divided every 6 hours.

Maximum dose: 4 g/day.

Usual Pediatric Dose for Skin and Structure Infection:

The dosage has not been established in pediatric patients less than 1 year old. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

1 year to 18 years: 50 to 100 mg/kg/day orally divided every 6 hours.

Maximum dose: 4 g/day.

How is cloxacillin available?

Cloxacillin is available in the following dosage forms and strengths:

  • Capsule 250 mg; 500 mg
  • Powder 250 mg; 500 mg
  • Solution 125 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of cloxacillin , take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 4, 2017 | Last Modified: January 4, 2017

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