Claforan

By Medically reviewed by hellodoktor

Generic Name: Claforan Brand Name(s): Claforan.

Uses

What is Claforan® (cefotaxime) used for?

Claforan® is a cephalosporin antibiotic under the powder form for injection. It is commonly used for treating a wide variety of bacterial infections by stopping the growth of bacteria.

How should I take Claforan® (cefotaxime)?

For injection form, you should:

  • Receive Claforan® injected by health care professional in hospital by a dose calculated by your doctor.
  • Read the label carefully before using Claforan®.
  • Consult your doctor for any information on the label that you do not clearly understand.

How do I store Claforan® (cefotaxime)?

Claforan® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Claforan® in the bathroom or the freezer. There may be different brands of Claforan® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Claforan® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

 

Precautions & warnings

What should I know before using Claforan® (cefotaxime)?

Before using Claforan®, tell your doctor if you have:

  • Allergic reaction to excipients using for dosage form containing Claforan® and other cephalosporin antibiotics such as:
  • Cefaclor (Raniclor)
  • Cefadroxil (Duricef)
  • Cefazolin (Ancef)
  • Cefdinir (Omnicef)
  • Cefditoren (Spectracef)
  • Cefpodoxime (Vantin)
  • Cefprozil (Cefzil)
  • Ceftibuten (Cedax)
  • Cefuroxime (Ceftin)
  • Cephalexin (Keflex)
  • Cephradine (Velosef))
  • Allergic reaction to any other medicines, foods, dyes, preservatives, or animals.
  • Used any other health conditions, drugs that interact with Claforan®.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Claforan® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Claforan®. Claforan® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Claforan® (cefotaxime)?

As taking others medicines, taking Claforan® can cause some side effects. Most of them are rarely occurring and do not need any supplementary treatment. However, it is always important for you to consult your doctor if you have any problem after taking this medicine.

Some of side effects are listed below:

  • Diarrhea (watery or bloody)
  • Skin rash
  • Bruising
  • Severe tingling
  • Numbness
  • Pain
  • Muscle weakness
  • Uneven heartbeats
  • Fever
  • Chills
  • Body aches
  • Flu symptoms
  • Easy bruising or bleeding
  • Unusual weakness
  • Fever, sore throat, and headache with a severe blistering, peeling, and red skin rash
  • Seizure (black-out or convulsions)
  • Jaundice (yellowing of the eyes or skin)
  • Pain, irritation, or a hard lump where the injection was given
  • Stomach pain
  • Nausea
  • Vomiting
  • Headache
  • Vaginal itching or discharge

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Claforan® (cefotaxime)?

Claforan® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, such as:

  • Warfarin
  • Probenecid

Does food or alcohol interact with Claforan® (cefotaxime)?

Claforan® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Claforan® (cefotaxime)?

Claforan® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Blood or bone marrow problems (e.g., agranulocytosis, granulocytopenia)
  • Colitis (inflammation in gut)
  • Severe diarrhea
  • Kidney disease

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Claforan® (cefotaxime).

What is the dose of Claforan® (cefotaxime) for an adult?

Consult your doctor for information about the dose of Claforan®.

Recommended doses in some cases are listed below:

  • For bacteremia: 1 to 2 g IV every 6 to 8 hours. The maximum dose is 2 g IV every 4 hours for a duration of 14 days.
  • For cesarean section: 1 g IV as soon as the umbilical cord is clamped. The second and third doses should be given as 1 g IV or IM at 6 and 12 hours after the first dose.
  • For CNS infection: 2 g IV every 4 to 6 hours.
  • For endometritis: 1 to 2 g IV or IM every 8 hours.
  • For epiglottitis: 2 g IV every 6 to 8 hours. The maximum dose is 2 g IV every 4 hours for a duration of 7 to 10 days.
  • For intra-abdominal infection: 1 to 2 g IV or IM every 6 to 8 hours. The maximum dose is 2 g IV every 4 hours for a duration of 7 to 14 days.
  • For joint infection: 1 to 2 g IV or IM every 6 to 8 hours. The maximum dose is 2 g IV every 4 hours. Treatment duration is 1 to 4 weeks, depending on the nature and severity of the infection. In some case, longer therapy can be applied, 6 weeks or more, may be required for prosthetic joint infections.
  • For Lyme disease – arthritis: 2 g IV every 8 hours. Treatment duration is 14 to 28 days.
  • For Lyme disease – carditis: 2 g IV every 8 hours. Treatment duration is 14 to 21 days.
  • For Lyme disease – neurologic: 2 g IV every 8 hours. Treatment duration is 14 to 28 days.
  • For meningitis: 2 g IV every 4 to 6 hours, depending on the nature and severity of the infection for approximately 14 days, depending on the nature and severity of the infection.
  • For osteomyelitis: 1 to 2 g IV or IM every 6 to 8 hours. The maximum dose is recommended to be 2 g IV every 4 hours. Treatment duration is 4 to 6 weeks.
  • For pelvic inflammatory disease: 1 to 2 g IV or IM every 6 to 8 hours. The maximum dose is recommended to be 2 g IV every 4 hours. Treatment duration is approximately 14 days, depending on the nature and severity of the infection.

What is the dose of Claforan® (cefotaxime) for a child?

Consult your doctor for information about the dose of Claforan®.

Recommended doses in some cases are listed below:

Children less than 13 years

For Early Lyme disease with neurologic involvement, Lyme arthritis with neurologic involvement, or late neuroborreliosis, 150 to 200 mg/kg/day IV is in 3 or 4 divided doses. The maximum dose is recommended to be 6 g/day. Treatment duration is 14 to 28 days.

Children from 13 years

Use adult dosage.

How is Claforan® (cefotaxime) available?

Claforan® is available in the following dosage forms and strengths:

  • Powder for infection: 1g, 2 g, 10 g.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Claforan®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 7, 2017 | Last Modified: September 13, 2019

Want to live your best life?
Get the Hello Doktor Daily newsletter for health tips, wellness updates and more.