Chlor-Trimeton

By Medically reviewed by hellodoktor

Generic Name: Chlor-Trimeton Brand Name(s): Generics only. No brands available.

Uses

What is Chlor-Trimeton® (Chlorpheniramine) used for?

Chlor-Trimeton® is commonly used for relieving symptoms of sinus congestion, sinus pressure, runny nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (e.g., colds), allergies, and hay fever. It may also be used for other conditions as determined by your doctor.

Chlor-Trimeton® is an antihistamine. It works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Chlor-Trimeton® (Chlorpheniramine).

What is the dose of Chlor-Trimeton® (Chlorpheniramine) for an adult?

  • Tablets or syrup: 4 mg PO q4-6hr; not to exceed 24 mg/day.
  • Extended-release tablets: 8 mg PO q8-12hr or 12 mg q12hr; not to exceed 24 mg/day.
  • Extended-release capsules: 12 mg PO qday; not to exceed 24 mg/day.
  • Sustained-release capsules: 8-12 mg PO q8-12hr, up to 16-24 mg/day.

What is the dose of Chlor-Trimeton® (Chlorpheniramine) for a child?

  • <2 years: safety & efficacy not established.
  • 2-6 years: 1 mg PO q4-6hr; not to exceed 6 mg/day.
  • 6-12 years: 2 mg PO q4-6hr; not to exceed 12 mg/day or sustained release HS.
  • >12 years
    • Tablets or syrup: 4 mg PO q4-6hr; not to exceed 24 mg/day.
    • Extended-release tablets: 8 mg PO q8-12hr or 12 mg q12hr; not to exceed 24 mg/day.
    • Extended-release capsules: 12 mg PO qday; not to exceed 24 mg/day.
    • Sustained-release capsules: 8-12 mg PO q8-12hr, up to 16-24 mg/day.

What is the dose of Chlor-Trimeton® (Chlorpheniramine) for geriatric?

  • 4 mg PO qDay or q12hr.
  • Sustained-release: 8 mg PO qHS.

Non-anticholinergic antihistamines should be considered first when treating allergic reactions (Beers Criteria).

Avoid use in elderly because of high incidence of anticholinergic effects.

Clearance reduced with advanced age, greater risk of confusion, dry mouth, constipation, and other anticholinergic effects and toxicity.

May exacerbate existing lower urinary conditions or benign prostatic hyperplasia.

Directions

How should I take Chlor-Trimeton® (Chlorpheniramine)?

  • If you are taking the over-the-counter product, read all directions on the product package before taking this medication. If you have any questions, consult your pharmacist. If your doctor has prescribed this medication, take it as directed.
  • Take the tablet, capsule, or liquid form by mouth with or without food. Follow the directions for dosing on the label, or take as directed by your doctor. This medication may be taken with food or milk if stomach upset occurs.
  • If you are taking the extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
  • If you are using the liquid form, use a medication measuring device to carefully measure the prescribed dose. Do not use a household spoon. If your liquid form is a suspension, shake the bottle well before each dose.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Chlor-Trimeton®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Side effects

What side effects can occur from Chlor-Trimeton® (Chlorpheniramine)?

Drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat may occur. These effects may decrease as your body adjusts to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

Chlorpheniramine can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.

Precautions/Warnings

What should I know before using Chlor-Trimeton® (Chlorpheniramine)?

Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • If you have allergies to medicines, foods, or other substances.
  • If you have a fast, slow, or irregular heartbeat.
  • If you have a history of asthma, lung problems (e.g., emphysema), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid.

Is it safe in specific conditions (e.g. pregnancy, breastfeeding, or surgery)?

Lactation: excretion in milk unknown/not recommended.

Pregnancy category: C

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Interactions

What drugs may interact with Chlor-Trimeton® (Chlorpheniramine)?

Some products that may interact with this drug include:

  • Antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray);
  • Antispasmodics (e.g., atropine, belladonna alkaloids);
  • Drugs for Parkinson’s disease (e.g., anticholinergics such as benztropine, trihexyphenidyl);
  • Scopolamine;
  • Tricyclic antidepressants (e.g., amitriptyline).

Keep a list of all the products you use (including prescription/nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does food or alcohol interact with Chlor-Trimeton® (Chlorpheniramine)?

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

How do I store Chlor-Trimeton® (Chlorpheniramine)?

Chlor-Trimeton® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Chlor-Trimeton® in the bathroom or the freezer. There may be different brands of Chlor-Trimeton® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Chlor-Trimeton® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

How is Chlor-Trimeton® (Chlorpheniramine) available?

Chlor-Trimeton® is available in the following dosage forms and strengths:

  • Chlor-trimeton® 12hour tablet, extended release: 12mg chlorpheniramine maleate.
  • Chlor-Trimeton® allergy, 4hour tablets, 24 tablets: 4mg chlorpheniramine maleate.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: December 1, 2016 | Last Modified: September 12, 2019

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