Cefpodoxime

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Generic Name: Cefpodoxime Brand Name(s): Generics only. No brands available.

Uses

What is cefpodoxime used for?

Cefpodoxime is a cephalosporin antibiotic that treats a wide variety of bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

How should I take cefpodoxime?

  • Take cefpodoxime by mouth with food.
  • Cefpodoxime works best if it is taken at the same time each day.
  • To clear up your infection completely, take cefpodoxime for the full course of treatment. Keep taking it even if you feel better in a few days.
  • Cefpodoxime should not be given within 2 hours of antacids or H2 antagonists (e.g., famotidine).
  • Ask your health care provider any questions you may have about how to use cefpodoxime.

How do I store cefpodoxime?

Cefpodoxime is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store cefpodoxime in the bathroom or the freezer. There may be different brands of cefpodoxime that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush cefpodoxime down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

 

Precautions & warnings

What should I know before using cefpodoxime?

Do not use cefpodoxime if you are allergic to any ingredient in cefpodoxime or to any other cephalosporin antibiotic (e.g., cephalexin, cefprozil)

Contact your doctor or health care provider right away if any of these apply to you.

Is it safe during pregnancy or breastfeeding?

Pregnancy

There are no adequate studies in women for determining risk when using cefpodoxime during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking cefpodoxime. Cefpodoxime is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Breastfeeding

The medicine is found in breast milk. Do not breastfeed while taking cefpodoxime.

Side effects

What side effects can occur from cefpodoxime?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Diarrhea
  • Headache
  • Loose stools
  • Nausea
  • Upset stomach
  • Vomiting

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Bloody stools
  • Seizures
  • Severe diarrhea
  • Skin rash
  • Stomach pain/cramps
  • Vaginal irritation or discharge

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Interactions

What drugs may interact with cefpodoxime?

Cefpodoxime may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some medicines may interact with cefpodoxime.

  • Aminoglycosides (e.g., gentamicin)
  • Cyclosporine
  • Diuretics (e.g., furosemide, hydrochlorothiazide)

Does food or alcohol interact with cefpodoxime?

Cefpodoxime may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with cefpodoxime?

Cefpodoxime may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Tell your doctor if you have:

  • Diarrhea
  • A stomach
  • Intestinal infection
  • A blood clotting problem
  • A severe allergic reaction (e.g., severe rash, hives, difficulty breathing, dizziness) to a penicillin antibiotic (e.g., amoxicillin) or other beta-lactam antibiotic (e.g., imipenem)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using cefpodoxime.

What is the dose of cefpodoxime for an adult?

Usual adult dose for bronchitis

Acute bacterial exacerbation of chronic bronchitis: 200 mg orally every 12 hours for 10 days.

Usual adult dose for cystitis

100 mg orally every 12 hours for 7 days.

Usual adult dose for gonococcal infection – uncomplicated

Uncomplicated urethral, cervical, or female anorectal infections: 200 mg orally one time.

Cefpodoxime is not indicated for pharyngeal N gonorrhoeae infections.

Usual adult dose for gonococcal infection – disseminated

400 mg orally twice a day.

Usual adult dose for pneumonia

Community-acquired pneumonia: 200 mg orally every 12 hours for 14 days.

Usual adult dose for pyelonephritis

100 mg orally every 12 hours.

Therapy should be continued for about 14 days, depending on the nature and severity of the infection.

Usual adult dose for sinusitis

200 mg orally every 12 hours for 10 days.

Usual adult dose for skin or soft tissue infection

Uncomplicated infection: 400 mg orally every 12 hours for 7 to 14 days.

Usual adult dose for tonsillitis/pharyngitis

100 mg orally every 12 hours for 5 to 10 days.

There are insufficient data to establish efficacy in the subsequent prophylaxis of rheumatic fever.

Usual adult dose for upper respiratory tract infection

100 mg orally every 12 hours.

Therapy should be continued for approximately 10 to 14 days, depending on the nature and severity of the infection.

What is the dose of cefpodoxime for a child?

Usual pediatric dose for bronchitis

Acute bacterial exacerbation of chronic bronchitis:

12 years or older: 200 mg orally every 12 hours for 10 days.

Usual pediatric dose for cystitis

12 years or older: 100 mg orally every 12 hours for 7 days.

Usual pediatric dose for gonococcal infection – uncomplicated

Uncomplicated urethral, cervical, or female anorectal infections:

12 years or older: 200 mg orally one time.

Cefpodoxime is not indicated for pharyngeal N gonorrhoeae infections.

Usual pediatric dose for gonococcal infection – disseminated

12 years or older: 400 mg orally twice a day.

Usual pediatric dose for otitis media

2 months through 12 years: 5 mg/kg/dose (maximum 200 mg) orally every 12 hours for 5 days.

Maximum dose: 400 mg/day.

Usual pediatric dose for pneumonia

Community-acquired pneumonia:

12 years or older: 200 mg orally every 12 hours for 14 days.

Usual pediatric dose for sinusitis

2 months through 12 years: 5 mg/kg/dose (maximum 200 mg) orally every 12 hours for 10 days.

Maximum dose: 400 mg/day.

12 years or older: 200 mg orally every 12 hours for 10 days.

Usual pediatric dose for skin or soft tissue infection

Uncomplicated infection:

12 years or older: 400 mg orally every 12 hours for 7 to 14 days.

Usual pediatric dose for tonsillitis/pharyngitis

2 months through 12 years: 5 mg/kg/dose (maximum 100 mg) orally every 12 hours for 5 to 10 days.

Maximum dose: 200 mg/day.

12 years or older: 100 mg orally every 12 hours for 5 to 10 days.

There are insufficient data to establish efficacy in the subsequent prophylaxis of rheumatic fever.

How is cefpodoxime available?

Cefpodoxime is available in the following dosage forms and strengths:

  • Cefpodoxime tablet 100mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of cefpodoxime, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: December 25, 2016 | Last Modified: January 4, 2017

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