Generic Name: Cefpirome Brand Name(s): Generics only. No brands available.

Uses

What is cefpirome used for?

Cefpirome is commonly used for treating susceptible infections. It works by fighting against the bacteria in your body.

How should I take cefpirome?

This drug is injected by your doctor (intravenous).

How do I store cefpirome?

Cefpirome is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store cefpirome in the bathroom or the freezer. There may be different brands of cefpirome that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush cefpirome down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using cefpirome?

Before using this drug, tell your doctor if:

  • You are allergic to any ingredients of this drug.
  • You have allergy to penicillin or to cephalosporins.
  • You have renal impairment, monitor renal and hematological status.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using cefpirome during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking cefpirome. Cefpirome is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Lactation:

This drug is excreted in breast milk; unsure if safe; do not use.

Side effects

What side effects can occur from cefpirome?

There are some side effects occurring while using cefpirome, such as:

  • Rash
  • Pruritus
  • Urticaria
  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Increased plasma levels of ASAT, ALAT, gamma-GT, LDH, bilirubin and/or alkaline phosphatase
  • Interstitial nephritis
  • Acute renal failure
  • Thrombocytopaenia
  • Eosinophilia
  • Hemolytic anemia
  • Neutropaenia
  • Agranulocytosis
  • Pain at injected site
  • Convulsions
  • Fever
  • Haemorrhage
  • Pseudomembranous colitis (potentially fatal)

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with cefpirome?

Cefpirome may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with cefpirome?

Cefpirome may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with cefpirome?

Cefpirome may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using cefpirome.

What is the dose of cefpirome for an adult?

The recommended dose is 1-4 g IV q12hr.

Renal impairment

  • CrCl 20-50 ml/min: 1-2 g load, 0.5-1 g IV BID
  • CrCl 5-20 ml/min: 1-2 g load, 0.5-1 g IV qDay
  • CrCl <5 ml/min 0.25-0.5 g qDay

Other information

Inject or infuse over 30 minutes.

What is the dose of cefpirome for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is cefpirome available?

Cefpirome is available in the following dosage forms and strengths:

  • Cefpirome 250mg tablets
  • Cefpirome 500mg tablets
  • Cefpirome 1g tablets

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of cefpirome, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: April 1, 2017 | Last Modified: April 1, 2017

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