Generic Name: Cardizem Brand Name(s): Generics only. No brands available.

Uses

What is Cardizem® (diltiazem) used for?

Cardizem® is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

Cardizem® is used to treat hypertension (high blood pressure). It may be used alone or in combination with other high blood pressure medications.

Cardizem® is also used to treat chronic stable angina (chest pain) and angina due to coronary artery spasm.

How should I take Cardizem® (diltiazem)?

Take Cardizem® exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole.

Use Cardizem® regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

You should not stop using Cardizem® suddenly. Stopping suddenly may make your condition worse.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your blood pressure will need to be checked often. You may also need frequent blood tests.

How do I store Cardizem® (diltiazem)?

Cardizem® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Cardizem® in the bathroom or the freezer. There may be different brands of Cardizem® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Cardizem® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Cardizem® (diltiazem)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Cardizem® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

You should not use Cardizem® if you have:

  • A serious heart condition such as “sick sinus syndrome” or “AV block” (unless you have a pacemaker)
  • Very low blood pressure
  • If you have recently had a heart attack and you have a build-up of fluid in your lungs

To make sure Cardizem® is safe for you, tell your doctor if you have:

  • Kidney disease
  • Liver disease

Congestive heart failure

  • If you also take digoxin, or a beta blocker (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others)

Cardizem® may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Do not stop taking this medication without first talking to your doctor. If you stop taking this medicine suddenly, your condition may become worse.

Cardizem® may be only part of a complete program of treatment that also includes diet, exercise, and other medications. Follow your diet, medication, and exercise routines very closely.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Cardizem® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Cardizem®. Cardizem® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Cardizem® (diltiazem)?

Get emergency medical help if you have signs of an allergic reaction to Cardizem®: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • Slow heartbeats
  • Pounding heartbeats or fluttering in your chest
  • A light-headed feeling, like you might pass out
  • Heart problems – shortness of breath (even with mild exertion), swelling, rapid weight gain
  • Liver problems – nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • Severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Common side effects may include:

  • Dizziness, weakness
  • Headache
  • Nausea
  • Rash

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Cardizem® (diltiazem)?

Cardizem® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Cardizem® (diltiazem)?

Cardizem® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Cardizem® (diltiazem)?

Cardizem® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Cardizem® (diltiazem).

What is the dose of Cardizem® (diltiazem) for an adult?

Exertional Angina Pectoris Due to Atherosclerotic Coronary Artery Disease or Angina Pectoris at Rest Due to Coronary Artery Spasm:

Dosage must be adjusted to each patient’s needs.

Starting with 30 mg four times daily, before meals and at bedtime, dosage should be increased gradually (given in divided doses three or four times daily) at 1- to 2-day intervals until optimum response is obtained.

Although individual patients may respond to any dosage level, the average optimum dosage range appears to be 180 to 360 mg/day.

There are no available data concerning dosage requirements in patients with impaired renal or hepatic function. If the drug must be used in such patients, titration should be carried out with particular caution.

What is the dose of Cardizem® (diltiazem) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Cardizem® (diltiazem) available?

Cardizem® is available in the following dosage forms and strengths:

  • Tablet, coated: Diltiazem Hydrochloride 30mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Cardizem®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: August 25, 2017 | Last Modified: August 25, 2017

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