Buspirone

By Medically reviewed by hellodoktor

Generic Name: Buspirone Brand Name(s): Buspirone.

Uses

What is buspirone used for?

Buspirone is commonly used to treat anxiety. It may help you think more clearly, relax, worry less, and take part in everyday life. It may also help you to feel less jittery and irritable, and may control symptoms such as trouble sleeping, sweating, and pounding heartbeat.

Buspirone is a medication for anxiety (anxiolytic) that works by affecting certain natural substances in the brain (neurotransmitters).

How should I take buspirone?

Take this medication by mouth, usually 2 or 3 times a day or as directed by your doctor. You may take this medication with or without food, but it is important to choose one way and always take it the same way so that the amount of drug absorbed will always be the same.

Buspirone may come in a tablet that can be split to get the correct dose for you.

Limit the amount of grapefruit you may eat or drink (less than one quart a day) while being treated with this medication unless your doctor directs you otherwise. Grapefruit may increase the amount of buspirone in your bloodstream. Consult your pharmacist or doctor for more information.

Dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. When this medication is started, symptoms of anxiety (e.g., restlessness) may sometimes get worse before they improve. It may take up to a month or more to get the full effect of this medication.

Inform your doctor if your symptoms persist or worsen.

How do I store buspirone?

Buspirone is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store buspirone in the bathroom or the freezer. There may be different brands of buspirone that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush buspirone down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using buspirone?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of buspirone or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Tell your doctor if you have or have ever had kidney or liver disease or a history of alcohol or drug abuse.

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking buspirone, call your doctor.

If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking buspirone.

You should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.

Remember that alcohol can add to the drowsiness caused by this drug.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using buspirone during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking buspirone. Buspirone is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from buspirone?

Common side effects include dizziness, nausea, headache, nervousness, lightheadedness, excitement, and insomnia.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • Chest pain
  • Feeling short or breath
  • Feeling like you might pass out

Other common side effects may include:

  • Dizziness, headache, blurred vision
  • Drowsiness, feeling tired
  • Feeling restless or nervous
  • Nausea, dry mouth, upset stomach
  • Sleep problems (insomnia), strange dreams
  • Stuffy nose, sore throat
  • Ringing in your ears

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with buspirone?

Buspirone may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with buspirone?

Buspirone may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with buspirone?

Buspirone may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using buspirone.

What is the dose of buspirone for an adult?

Usual Adult Dose for Anxiety

Initial dose: 7.5 mg orally two times a day or 5 mg 3 times a day.

Maintenance dose: The daily dose may be increased in 5 mg increments every 2 to 3 days up to 20 to 60 mg/day in divided doses.

Maximum dose: 60 mg per day.

What is the dose of buspirone for a child?

Usual Pediatric Dose for Anxiety

6 to 18 years:

Initial dose: 2.5 to 10 mg daily.

Maintenance dose: The daily dose may be increased in 2.5 mg increments every 2 to 3 days to 15 to 60 mg/day given in 2 divided doses.

How is buspirone available?

Buspirone is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of buspirone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: July 18, 2017 | Last Modified: September 13, 2019

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