Bufferin

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Generic Name: Bufferin Brand Name(s): Generics only. No brands available.

Uses

What is Bufferin® (aspirin) used for?

Bufferin® is commonly used for treating pain, and reducing fever or inflammation. Bufferin® is sometimes used to treat or prevent heart attacks, strokes, and chest pain (angina). Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.

Aspirin may also be used for purposes not listed in this medication guide.

How should I take Bufferin® (aspirin)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take with food if aspirin upsets your stomach.

Do not crush, chew, break, or open an enteric-coated or delayed-release pill. Swallow it whole.

The chewable tablet form of aspirin must be chewed before swallowing.

If you use the orally disintegrating tablet or the dispersible tablet, follow all dosing instructions provided with your medicine.

If you need surgery, tell the surgeon ahead of time that you are using aspirin. You may need to stop using the medicine for a short time.

Do not take this medicine if you smell a strong vinegar odor in the aspirin bottle. The medicine may no longer be effective.

How do I store Bufferin® (aspirin)?

Bufferin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Bufferin® in the bathroom or the freezer. There may be different brands of Bufferin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Bufferin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Bufferin® (aspirin)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Bufferin® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

You should not use aspirin if you have a bleeding disorder such as hemophilia, a recent history of stomach or intestinal bleeding, or if you are allergic to an NSAID (non-steroidal anti-inflammatory drug).

Aspirin can cause Reye’s syndrome, a serious and sometimes fatal condition in children.

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye’s syndrome, a serious and sometimes fatal condition in children.

You should not use aspirin if you are allergic to it, or if you have:

  • A recent history of stomach or intestinal bleeding
  • A bleeding disorder such as hemophilia
  • An asthma attack or severe allergic reaction after taking aspirin or an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Bufferin® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Bufferin®.

Side effects

What side effects can occur from Bufferin® (aspirin)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using aspirin and call your doctor at once if you have:

  • Ringing in your ears, confusion, hallucinations, rapid breathing, seizure (convulsions)
  • Severe nausea, vomiting, or stomach pain
  • Bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
  • Fever lasting longer than 3 days
  • Swelling, or pain lasting longer than 10 days

Common side effects may include:

  • Upset stomach, heartburn
  • Drowsiness
  • Mild headache

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Bufferin® (aspirin)?

Bufferin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • A blood thinner (warfarin, Coumadin, Jantoven), or other medication used to prevent blood clots
  • Other salicylates such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others

Does food or alcohol interact with Bufferin® (aspirin)?

Bufferin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Bufferin® (aspirin)?

Bufferin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Asthma or seasonal allergies
  • Stomach ulcers
  • Liver disease
  • Kidney disease
  • A bleeding or blood clotting disorder
  • Gout
  • Heart disease, high blood pressure, or congestive heart failure

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Bufferin® (aspirin).

What is the dose of Bufferin® (aspirin) for an adult?

Usual Adult Dose for Osteoarthritis

Initial dose: 3 g orally per day in divided doses

Maintenance: Adjust dose as needed for anti-inflammatory efficacy

Usual Adult Dose for Rheumatoid Arthritis

Initial dose: 3 g orally per day in divided doses

Maintenance: Adjust dose as needed for anti-inflammatory efficacy

Usual Adult Dose for Systemic Lupus Erythematosus

Initial dose: 3 g orally per day in divided doses

Maintenance: Adjust dose as needed for anti-inflammatory efficacy

Usual Adult Dose for Fever

Oral:

  • 300 to 650 mg orally every 4 to 6 hours as needed
  • Maximum dose: 4 g in 24 hours

Rectal:

  • 300 to 600 mg rectally every 4 hours

Usual Adult Dose for Pain

Oral:

  • 300 to 650 mg orally every 4 to 6 hours as needed
  • Maximum dose: 4 g in 24 hours

Rectal:

  • 300 to 600 mg rectally every 4 hours

Usual Adult Dose for Myocardial Infarction

Immediate-Release:

Initial dose: 160 to 162.5 mg orally once as soon as myocardial infarction is suspected

Maintenance dose: 160 to 162.5 mg orally once a day for 30 days post-infarction

Usual Adult Dose for Ischemic Stroke

Immediate-release: 50 to 325 mg orally once a day

Extended-release (ER): 162.5 mg orally once a day

Usual Adult Dose for Ischemic Stroke – Prophylaxis

Immediate-release: 50 to 325 mg orally once a day

Extended-release (ER): 162.5 mg orally once a day

Usual Adult Dose for Angina Pectoris Prophylaxis

Immediate-release (IR): 75 mg to 325 mg orally once a day

Extended-release (ER): 162 mg orally once a day

Usual Adult Dose for Angina Pectoris

Immediate-release (IR): 75 mg to 325 mg orally once a day

Extended-release (ER): 162 mg orally once a day

Usual Adult Dose for Revascularization Procedures – Prophylaxis

For coronary artery bypass graft (CABG): 325 mg orally once a day beginning 6 hours after the procedure and continuing for 1 year

For percutaneous transluminal coronary angiography (PTCA): 325 mg orally once 2 hours prior to procedure, then 160 to 325 mg orally once a day indefinitely

For carotid endarterectomy: 80 mg orally once a day up to 650 mg orally twice a day beginning prior to surgery and continuing indefinitely

Usual Adult Dose for Ankylosing Spondylitis

Up to 4 g orally per day in divided doses

Maintenance dose: Adjust dose as needed for anti-inflammatory efficacy

Usual Adult Dose for Myocardial Infarction – Prophylaxis

Primary Prophylaxis:

  • 50 years or older: 75 to 100 mg orally once a day
  • Adults with type 1 or type 2 diabetes at increased CVD risk: 75 to 162 mg orally once a day

Usual Adult Dose for Cardiovascular Risk Reduction

Primary Prophylaxis:

  • 50 years or older: 75 to 100 mg orally once a day
  • Adults with type 1 or type 2 diabetes at increased CVD risk: 75 to 162 mg orally once a day

Usual Adult Dose for Colorectal Cancer

50 years or older: 75 to 100 mg orally once a day

What is the dose of Bufferin® (aspirin) for a child?

Usual Pediatric Dose for Fever

12 years or older: 300 to 650 mg orally every 4 to 6 hours as needed

Maximum dose: 4 g in 24 hours

Usual Pediatric Dose for Pain

12 years or older: 300 to 650 mg orally every 4 to 6 hours as needed

Maximum dose: 4 g in 24 hours

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis

Initial dose: 90 to 130 mg/kg orally in divided doses

Maintenance dose: Increase as needed for anti-inflammatory efficacy.

Usual Pediatric Dose for Kawasaki Disease

Initial (acute phase): 80 to 100 mg/kg orally in divided doses for up to 14 days (as an anti-inflammatory agent)

Followed by: 1 to 5 mg/kg orally per day for 6 to 8 weeks (as an antiplatelet agent)

Usual Pediatric Dose for Thrombotic/Thromboembolic Disorder

1 to 5 mg/kg orally per day.

How is Bufferin® (aspirin) available?

Bufferin® is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Bufferin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: October 5, 2017 | Last Modified: October 5, 2017

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