Generic Name: Augmentin Brand Name(s): Generics only. No brands available.

Uses

What is augmentin® (amoxicillin and clavulanate potassium) used for?

Augmentin® is commonly used for the treatment of many different infections caused by bacteria, such as sinusitis, pneumonia, ear infections, bronchitis, urinary tract infections, and infections of the skin.

How should I take augmentin® (amoxicillin and clavulanate potassium)?

Take augmentin® exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

If you switch from one tablet form to another (regular, chewable, or extended-release tablet), take only the new tablet form and strength prescribed for you.

Take this medicine with a full glass of water. Take the medicine at the start of a meal to reduce stomach upset.

Take the medicine at the same time each day.

The augmentin® tablet should be swallowed whole.

The augmentin® chewable tablet must be chewed before swallowing. Do not swallow a chewable tablet whole.

Do not crush or chew the augmentin® XR (extended-release) tablet. Swallow the pill whole, or break the pill in half and take both halves one at a time.

Shake the liquid form of this medicine well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Take augmentin® for the full prescribed length of time.

How do I store augmentin® (amoxicillin and clavulanate potassium)?

Tablets

Augmentin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store augmentin® in the bathroom or the freezer. There may be different brands of augmentin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush augmentin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Liquid

Augmentin® is best stored in the refrigerator. To prevent drug damage, do not freeze. There may be different brands of augmentin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush augmentin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product. Throw away any unused liquid after 10 days.

Precautions & warnings

What should I know before using augmentin® (amoxicillin and clavulanate potassium)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of augmentin® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

If you switch from one tablet form to another (regular, chewable, or extended-release tablet), take only the new tablet form and strength prescribed for you. This medicine may not be as effective or could be harmful if you do not use the exact tablet form your doctor has prescribed.

Augmentin® can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking augmentin®.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using augmentin® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking augmentin®. Augmentin® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from augmentin® (amoxicillin and clavulanate potassium)?

Stop using this medicine and call your doctor at once if you have a serious side effect such as:

  • Diarrhea that is watery or has blood in it
  • Pale or yellowed skin
  • Dark colored urine
  • Fever
  • Confusion or weakness
  • Easy bruising or bleeding
  • Skin rash
  • Bruising
  • Severe tingling
  • Numbness
  • Pain
  • Muscle weakness
  • Agitation
  • Unusual thoughts or behavior
  • Seizure (convulsions)
  • Nausea
  • Upper stomach pain
  • Itching
  • Loss of appetite
  • Clay-colored stools

Get emergency medical help if you have any of these signs of an allergic reaction like hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with augmentin® (amoxicillin and clavulanate potassium)?

Augmentin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug, such as:

  • Cefdinir (Omnicef)
  • Cefprozil (Cefzil)
  • Cefuroxime (Ceftin)
  • Cephalexin (Keflex)

Does food or alcohol interact with augmentin® (amoxicillin and clavulanate potassium)?

Augmentin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with augmentin® (amoxicillin and clavulanate potassium)?

Augmentin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Tell your doctor if you have any of these other conditions:

  • Liver disease (or a history of hepatitis or jaundice)
  • Kidney disease
  • Mononucleosis

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using augmentin® (amoxicillin and clavulanate potassium).

What is the dose of augmentin® (amoxicillin and clavulanate potassium) for an adult?

Lower Respiratory Tract Infection

Mild to moderate: the recommended dose is 500/125 mg PO q12hr or 250/125 mg PO q8hr for 10 days.

Severe: the recommended dose is 875/125 mg PO q12hr or 500/125 mg PO q8hr or 2000 mg (2 extended-release tabs) PO q12hr for 7-10 days.

Chronic Obstructive Pulmonary Disease

The recommended dose is 500 mg PO q8hr.

Acute Bacterial Sinusitis

The recommended dose is 2000 mg (2 extended-release tablets) PO q12hr for 10 days.

Animal/Human Bite Wounds

The recommended dose is 875 mg PO q12hr or 500 mg PO q8hr for 3-5 days.

Erysipelas

The recommended dose is 875 mg PO q12hr or 500 mg PO q8hr for 7-10 days.

Pyelonephritis

The recommended dose is 875 mg PO q12hr or 500 mg PO q8hr.

Skin Abscess

The recommended dose is 875 mg PO q12hr.

Diabetic Foot

Mild to moderate, localized cellulitis

The recommended dose is 2000 mg (2 extended-release tablets) PO q12hr for 7-14 days.

Group A Streptococci, Chronic Carrier

The recommended dose is 40 mg/kg/day PO divided q8hr for 10 days; not to exceed 2000 mg/day.

What is the dose of augmentin® (amoxicillin and clavulanate potassium) for a child?

<40 kg: Dosages based on amoxicillin.

>40 kg: Dose according to adult recommendations.

<3 months old: The recommended dose is 30 mg/kg/day PO (125 mg/5 mL or chewable tablets) divided q12hr.

>3 months old

  • Less severe infections: The recommended dose is 20 mg/kg/day PO (125 mg/5 mL or 250 mg/5 mL) divided q8hr or 25 mg/kg/day PO (200 mg or 400 mg chewable tablets; 200 mg/5 mL or 400 mg/5 mL) divided q12hr.
  • Severe infections, lower respiratory tract infections, sinusitis, otitis media: The recommended dose is 40 mg/kg/day PO (125 mg/5 mL or 250 mg/5 mL) divided q8hr or 45 mg/kg/day PO (200 mg or 400 mg chewable tablets; 200 mg/5 mL or 400 mg/5 mL) divided q12hr.

Acute otitis media

The recommended dose is 80-90 mg/kg/day PO divided q12hr for 10 days (may be 5-7 days for children >6 years old with mild-to-moderate disease).

Mild to moderate infection

The recommended dose is 90 mg/kg/day PO divided q12hr; not to exceed 4000 mg/day.

H. Influenzae

The recommended dose is 45 mg/kg/day PO divided q8hr or 90 mg/kg/day PO divided q12hr.

How is augmentin® (amoxicillin and clavulanate potassium) available?

Augmentin® is available in the following dosage forms and strengths:

Oral suspension

  • (125mg/31.25mg)/5mL
  • (200mg/28.5mg)/5mL
  • (250mg/62.5mg)/5mL
  • (400mg/57mg)/5mL
  • (600mg/42.9mg)/5mL

Tablet

  • 200mg/28.5mg
  • 250mg/125mg
  • 500mg/125mg
  • 875mg/125mg
  • 1000mg/62.5mg

Tablet, chewable

  • 200 mg/28.5mg
  • 400 mg/57mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of augmentin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: June 7, 2017 | Last Modified: June 7, 2017

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