Generic Name: Apranax Brand Name(s): Generics only. No brands available.

Uses

What is Apranax ® (naproxen sodium) used for?

Apranax ® is a medicinal product containing a non-steroidal anti-inflammatory drug (NSAID) called naproxen sodium, commonly used for:

  • Relieving pain from various conditions such as headaches, muscle aches, tendonitis, dental pain, and menstrual cramps.
  • Reducing pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks.

How should I take Apranax ® (naproxen sodium)?

For orally taken form, you should:

  • Take Apranax ® bymouth as directed by your doctor concerning: dose, schedule.
  • Read the label carefully before using Apranax.
  • Consult your doctor for any information on the label that you do not clearly understand.

How do I store Apranax ® (naproxen sodium)?

Apranax ® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Apranax ® in the bathroom or the freezer. There may be different brands of Apranax ® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Apranax ® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Apranax ® (naproxen sodium)?

Before using Apranax ®, tell your doctor if:

  • You have allergic reaction to Apranax, excipients using for dosage form containing Apranax.
  • You have allergic reaction to any other medicines, foods, dyes, preservatives, or animals.
  • You have used any other health conditions, drugs that have a risk of interaction with Apranax ®.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Apranax ® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Apranax ®. Apranax ® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Apranoax ® (naproxen sodium)?

As taking others medicines, taking Apranax ® can cause some side effects. Most of them are rarely occurring and do not need any supplementary treatment. However, it is always important for you to consult your doctor if you have any problem after taking this medicine.

Some of side effects are:

  • Upset stomach, mild heartburn or stomach pain
  • Diarrhea
  • Constipation
  • Bloating, gas
  • Dizziness, headache, nervousness
  • Skin itching or rash
  • Blurred vision
  • Ringing in your ears
  • Chest pain
  • Weakness
  • Shortness of breath
  • Slurred speech
  • Problems with vision or balance
  • Black, bloody, or tarry stools
  • Coughing up blood or vomit (that looks like coffee grounds)
  • Swelling or rapid weight gain
  • Little or no urinating
  • Nausea
  • Itching
  • Loss of appetite
  • Dark urine
  • Jaundice (yellowing of the skin or eyes)
  • Bruising
  • Severe tingling
  • Numbness
  • Pain
  • Muscle weakness
  • Fever
  • Headache
  • Neck stiffness
  • Chills
  • Increased sensitivity to light
  • Purple spots on the skin
  • Seizure (convulsions)
  • Severe skin reaction

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Apranax ® (naproxen sodium)?

Apranax ® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Benazepril (Lotensin)
  • Captopril (Capoten)
  • Enalapril (Vasotec)
  • Fosinopril (Monopril)
  • Lisinopril (Prinivil, Zestril)
  • Moexipril (Univasc)
  • Perindopril (Aceon)
  • Quinapril (Accupril)
  • Ramipril (Altace)
  • Trandolapril (Mavik)
  • Angiotensin II receptor antagonists (angiotensin receptor blockers; ARBs) such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan)
  • Beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal)
  • Cholestyramine (Questran)
  • Diuretics (‘water pills’)
  • Lithium (Eskalith, Lithobid)
  • Medications for diabetes
  • Methotrexate (Rheumatrex)
  • Probenecid (Benemid)
  • Selective serotonin reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft)
  • Sulfa medications such as sulfamethoxazole (in Septra, Bactrim)
  • Warfarin (Coumadin)

Does food or alcohol interact with Apranax ® (naproxen sodium)?

Apranax ® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Apranax ® (naproxen sodium)?

Apranax ® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Anemia
  • Bleeding problems
  • Blood clots
  • Edema (fluid retention or body swelling)
  • Heart attack
  • Heart disease (e.g., congestive heart failure)
  • Hypertension (high blood pressure)
  • Kidney disease
  • Liver disease (e.g., hepatitis)
  • Stomach or intestinal ulcers or bleeding
  • Stroke
  • Aspirin-sensitive asthma
  • Aspirin sensitivity
  • Heart surgery (e.g., coronary artery bypass graft [CABG])

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Apranax®.

What is the dose of Apranax ® (naproxen sodium) for an adult?

Consult your doctor for information about dose of Apranax ®.

Recommended doses in some cases are listed below:

For ankylosing spondylitis:

  • The recommended initial dose is 275 mg to 550 mg orally twice a day.
  • The initial dose for naproxen sodium controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day.

For osteoarthritis:

  • The recommended initial dose is275 mg to 550 mg orally twice a day.
  • The initial dose for naproxen sodium controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day.

For rheumatoid arthritis:

  • The recommended initial dose is 275 mg to 550 mg (naproxen sodium) orally twice a day.
  • The initial dose for naproxen sodium controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day.

For acute gout:

  • The recommended initial dose is 750 mg (naproxen) or 825 mg (naproxen sodium) orally one time, followed by 250 mg (naproxen) or 275 mg (naproxen sodium) every 8 hours until the gouty attack has resolved, usually 2 to 3 days.
  • The recommended dose of naproxen sodium controlled-release is two to three 500 mg tablets (1000 to 1500 mg) orally on the first day, followed by two 500 mg tablets (1000 mg) orally daily until the attack has subsided.

For bursitis:

  • The recommended initial dose is 550 mg naproxen sodium orally once, followed by 550 mg naproxen sodium every 12 hours, or 275 mg (naproxen sodium)/250 mg (naproxen) every 6 to 8 hours as needed.
  • The recommended maximum daily dose is 1100 mg naproxen sodium or 1000 mg naproxen.
  • The recommended initial dose of naproxen sodium controlled-release is two 500 mg tablets (1000 mg) orally once a day.

For tendonitis:

  • The recommended initial dose is 550 mg naproxen sodium orally once, followed by 550 mg naproxen sodium every 12 hours, or 275 mg (naproxen sodium)/250 mg (naproxen) every 6 to 8 hours as needed.
  • The recommended maximum daily dose is 1100 mg naproxen sodium or 1000 mg naproxen.
  • The recommended initial dose of naproxen sodium controlled-release is two 500 mg tablets (1000 mg) orally once a day.

For dysmenorrhea:

  • The recommended initial dose is 550 mg naproxen sodium orally once, followed by 550 mg naproxen sodium every 12 hours, or 275 mg (naproxen sodium)/250 mg (naproxen) every 6 to 8 hours as needed.
  • The recommended maximum daily dose is 1100 mg naproxen sodium or 1000 mg naproxen.

For pain:

  • The recommended initial dose is 550 mg naproxen sodium orally once, followed by 550 mg naproxen sodium every 12 hours, or 275 mg (naproxen sodium)/250 mg (naproxen) every 6 to 8 hours as needed.
  • The recommended maximum daily dose is 1100 mg naproxen sodium or 1000 mg naproxen.

What is the dose of Apranax ® (naproxen sodium) for a child?

Consult your doctor for information about dose of Apranax ®.

Recommended doses in some cases are listed below:

For fever:

For children greater than 2 years, the recommend dose is 2.5 to 10 mg/kg/dose. The recommended maximum daily dose is 10 mg/kg, given every 8 to 12 hours.

For pain:

For children greater than 2 years, the recommend dose is 2.5 to 10 mg/kg/dose. The recommended maximum daily dose e is 10 mg/kg, given every 8 to 12 hours.

For juvenile rheumatoid arthritis

For children greater than or equal to 2 years, the recommend dose is 5 mg/kg orally twice a day. The recommended maximum daily dose is 1000 mg/day.

How is Apranax ® (naproxen sodium) available?

Apranax ® is available in the following dosage forms and strengths:

  • Tablet, Oral: 220 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Apranax ®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

 

Sources

Review Date: May 11, 2017 | Last Modified: May 11, 2017

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