Apixaban

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Generic Name: Apixaban Brand Name(s): Apixaban.

Uses

What is Apixaban used for?

Apixaban is commonly used to thin the blood so that clots will not form. It is used to treat blood clots.

How should I take Apixaban?

Use apixaban as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • If you have trouble swallowing this medicine, it can be crushed and mixed in water, apple juice, or applesauce. If you crush and mix apixaban, take it within 4 hours of mixing.
  • To gain the most benefit, do not miss doses.
  • Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well.
  • Those who have feeding tubes may use apixaban. Use as you have been told. Flush the feeding tube after this medicine is given.

How do I store Apixaban?

Apixaban is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Apixaban in the bathroom or the freezer. There may be different brands of Apixaban that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Apixaban down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Apixaban?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Apixaban or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have any of these health problems: Active bleeding or liver problems.
  • You have had a heart valve replaced.
  • You are taking any of these drugs: Carbamazepine, clarithromycin, itraconazole, ketoconazole, phenytoin, rifampin, ritonavir, St. John’s wort, telithromycin, or voriconazole.

Tell all of your health care providers that you take apixaban. This includes your doctors, nurses, pharmacists, and dentists. This medicine may need to be stopped before certain types of surgery as your doctor has told you. If this medicine is stopped, your doctor will tell you when to start taking apixaban again after your surgery or procedure.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

Do not run out of this medicine.

You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.

Very bad and sometimes deadly bleeding problems have happened with apixaban. Talk with the doctor.

If you fall or hurt yourself, or if you hit your head, call your doctor right away. Talk with your doctor even if you feel fine.

Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Apixaban during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Apixaban. Apixaban is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Apixaban?

Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
  • Dizziness or passing out.
  • Feeling tired or weak.
  • Feeling confused.
  • Headache
  • Joint pain or swelling.
  • Chest pain or pressure.
  • Wheezing

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Apixaban?

Apixaban may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Apixaban?

Apixaban may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Apixaban?

Apixaban may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Apixaban.

What is the dose of Apixaban for an adult?

Consult your doctor for further information.

What is the dose of Apixaban for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Apixaban available?

Apixaban is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Apixaban, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: November 17, 2017 | Last Modified: November 20, 2017

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