By Medically reviewed by hellodoktor

Generic Name: Antazoline Brand Name(s): Generics only. No brands available.


What is antazoline used for?

Antazoline is a 1st generation antihistamine that also anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.

How should I take antazoline?

Antazoline is available as eye drops. It is used as topical antihistamines /antipruritics.

Remove contact lenses before using.

How do I store antazoline?

Antazoline is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store antazoline in the bathroom or the freezer. There may be different brands of antazoline that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush antazoline down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using antazoline?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of antazoline or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have had an allergic reaction to an antihistamine or to any eye drops.
  • Your children under 6 years of age unless directed by a physician.

Do not use if you have the solution has changed color or becomes cloudy.

Transient burning and stinging have been reported with some patients upon instillation.

Overuse of this product may produce increased eye redness.

Avoid use on large areas of the skin. Do not use on broken or eczematous skin.

Is it safe during pregnancy or breastfeeding? 

There isn’t enough information about the safety of using antazoline during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking antazoline.

Side effects

What side effects can occur from antazoline?

Stop use and ask a doctor if you experience any of the following for more than 72 hours, including:

  • Eye pain
  • Changes in vision
  • Redness
  • Irritation

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with antazoline?

Antazoline may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with antazoline?

Antazoline may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with antazoline?

Antazoline may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Heart disease
  • High blood pressure
  • Narrow angle glaucoma


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using antazoline.

What is the dose of antazoline for an adult?

Instill 1 or 2 drops in the affected eye(s) as needed up to 4 times daily.

What is the dose of antazoline for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is antazoline available?

Antazoline is available in the following dosage forms and strengths:

  • Eye drops: 0.5 Fl oz. (15 mL) bottles.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of antazoline, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: October 10, 2017 | Last Modified: September 11, 2019

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