What is anidulafungin used for?
Anidulafungin is an antifungal medication that fights infections caused by fungus.
Anidulafungin treats candida (yeast) infections in the blood, or in the stomach or esophagus.
Anidulafungin may also be used for purposes not listed in this medication guide.
How should I take anidulafungin?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Anidulafungin is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Anidulafungin is a powder medicine that must be mixed with a liquid (diluent) before using it. You will then need to dilute this mixture into a solution with another liquid in an IV bag. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Anidulafungin is sometimes given for up to 14 days after lab tests show that the infection has cleared. Use this medicine for the full prescribed length of time. Anidulafungin will not treat a viral infection such as the flu or a common cold.
Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof “sharps” disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Do not use anidulafungin diluted solution if it has changed colors or has particles in it. Call your pharmacist for new medication.
How do I store anidulafungin?
Store the dry powder medicine in a refrigerator. Do not freeze.
After you mix the powder and diluent, you may store this mixture at room temperature for up to 24 hours before further diluting it. The final diluted solution may be stored at room temperature for up to 48 hours.
You may also store the diluted solution in a freezer for at least 72 hours before using it.
Precautions & warnings
What should I know before using anidulafungin?
Before using this drug, tell your doctor if:
- You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
- You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
- You have allergy with any of active or inactive ingredients of anidulafungin or other medications.
- You have any other illnesses, disorders, or medical conditions.
- You are allergic to anidulafungin, caspofungin (Cancidas), micafungin (Mycamine), or similar antifungal medicines.
- You have liver disease.
Is it safe during pregnancy or breastfeeding?
There are no adequate studies in women for determining risk when using anidulafungin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking anidulafungin. Anidulafungin is pregnancy risk category C, according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk
- B=No risk in some studies
- C=There may be some risk
- D=Positive evidence of risk
What side effects can occur from anidulafungin?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, itchy, sweaty, or if you have chest tightness or trouble breathing.
Call your doctor at once if you have:
- A light-headed feeling, like you might pass out
- Trouble breathing
- Pain or burning when you urinate
- Liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
- Low potassium–confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling
- Low red blood cells (anemia)–pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating
Common side effects may include:
- Upset stomach, nausea, vomiting, diarrhea
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with anidulafungin?
Anidulafungin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Does food or alcohol interact with anidulafungin?
Anidulafungin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with anidulafungin?
Anidulafungin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using anidulafungin.
What is the dose of anidulafungin for an adult?
Usual Adult Dose for Esophageal Candidiasis:
Initial dose: 100 mg IV on Day 1
Maintenance dose: 50 mg IV once a day thereafter
Duration: Treatment should be given for a minimum of 14 days and for at least 7 days following resolution of symptoms. Treatment duration should be based on the patient’s clinical response. If the patient is infected with HIV, suppressive antifungal therapy may be considered after a course of treatment to minimize the risk of relapse.
Usual Adult Dose for Candidemia:
Candidemia and other Candida infections (intraabdominal abscess and peritonitis):
Initial dose: 200 mg IV on Day 1
Maintenance dose: 100 mg IV once a day thereafter
Duration: Duration of treatment should be based on the patient’s clinical response. In general, antifungal therapy should continue for at least 14 days after the last positive culture.
What is the dose of anidulafungin for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is anidulafungin available?
Anidulafungin is available in the following dosage forms and strengths:
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of anidulafungin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Review Date: October 10, 2017 | Last Modified: October 10, 2017
Anidulafungin. https://www.drugs.com/mtm/anidulafungin.html. Accessed October 9, 2017
Anidulafungin. http://reference.medscape.com/drug/ecalta-eraxis-anidulafungin-342599. Accessed October 9, 2017