What is Amlodipine + Olmesartan used for?
This product contains 2 medications: amlodipine and olmesartan. They both work by relaxing blood vessels so blood can flow more easily. Amlodipine is a calcium channel blocker and olmesartan is an angiotensin receptor blocker (ARB).
How should I take Amlodipine + Olmesartan?
Take this medication by mouth with or without food as directed by your doctor, usually once daily.
The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.
If you also take certain drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine, colesevelam, colestipol), take amlodipine/olmesartan at least 4 hours before any of these medications.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take up to 2 weeks before you get the full benefit of this drug.
Tell your doctor if your condition does not improve or if it worsens (your blood pressure readings remain high or increase).
How do I store Amlodipine + Olmesartan?
Amlodipine + Olmesartan is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Amlodipine + Olmesartan in the bathroom or the freezer. There may be different brands of Amlodipine + Olmesartan that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Amlodipine + Olmesartan down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Amlodipine + Olmesartan?
Before taking this product, tell your doctor or pharmacist if you are allergic to either amlodipine or olmesartan, or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, a certain heart valve condition (aortic stenosis), severe loss of body water and minerals (dehydration).
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Too much sweating, diarrhea, or vomiting may cause you to feel lightheaded. Report prolonged diarrhea or vomiting to your doctor.
This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the side effects of this drug, especially dizziness and change in the amount of urine (kidney problems).
Is it safe during pregnancy or breast-feeding?
There are no adequate studies in women for determining risk when using this Amlodipine + Olmesartan during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this Amlodipine + Olmesartan. This Amlodipine + Olmesartan is pregnancy risk category D according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk,
- B=No risk in some studies,
- C=There may be some risk,
- D=Positive evidence of risk,
What side effects can occur from Amlodipine + Olmesartan?
Dizziness or lightheadedness may occur as your body adjusts to the medication. Headache or flushing may also occur. If any of these effects persists or worsens, tell your doctor or pharmacist promptly.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: swelling hands/ankles/feet, fainting, fast heartbeat, signs of kidney problems (such as change in the amount of urine), symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat), severe/persistent diarrhea.
Some people who already have severe heart disease may rarely develop worsening chest pain or a heart attack after starting this medication or increasing the dose. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Amlodipine + Olmesartan?
Amlodipine + Olmesartan may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Some products that may interact with this drug include: aliskiren, lithium, drugs that may increase the level of potassium in the blood (such as ACE inhibitors including benazepril/lisinopril, birth control pills containing drospirenone).
Some products have ingredients that could raise your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).
Does food or alcohol interact with Amlodipine + Olmesartan?
Amlodipine + Olmesartan may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Amlodipine + Olmesartan?
Amlodipine + Olmesartan may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Amlodipine + Olmesartan.
What is the dose of Amlodipine + Olmesartan for an adult?
Usual Adult Dose for Hypertension
Initial dose: Amlodipine 5 mg-Olmesartan 20 mg orally once a day; may increase dose after 1 to 2 weeks of therapy.
Maximum dose: Amlodipine 10 mg-Olmesartan 40 mg orally once a day
- Substitution therapy for patients maintained on the individual components separately or for patients not adequately controlled with one of the components or a component within the same antihypertensive class.
- Initial therapy in patients who are likely to need more than 1 antihypertensive agent to control blood pressure.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Initial therapy not recommended
What is the dose of Amlodipine + Olmesartan for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Amlodipine + Olmesartan available?
Amlodipine + Olmesartan is available in the following dosage forms and strengths:
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Amlodipine + Olmesartan, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Review Date: January 4, 2018 | Last Modified: September 12, 2019
Amlodipine-Olmesartan. https://www.webmd.com/drugs/2/drug-149214/amlodipine-olmesartan-oral/details. Accessed January 3, 2017.
Amlodipine / Olmesartan Dosage. https://www.drugs.com/dosage/amlodipine-olmesartan.html. Accessed January 3, 2017