By Medically reviewed by hellodoktor

Generic Name: Amisulpride Brand Name(s): Amisulpride, Amisulpride and Amisulpride.


What is amisulpride used for?

Amisulpride works by improving disturbed thoughts, feelings and behavior. It is used to treat Schizophrenia.

How should I take amisulpride?

Swallow amisulpride tablets with plenty of water before a meal.

Do not drink alcohol while you are taking amisulpride. This is because amisulpride can change the way the alcohol affects you.

How do I store amisulpride?

Amisulpride is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store amisulpride in the bathroom or the freezer. There may be different brands of amisulpride that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush amisulpride down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using amisulpride?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of amisulpride or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have breast cancer or something called “a prolactin dependent tumor”.
  • You have a tumor on your adrenal gland (called phaeochromocytoma).
  • You have been diagnosed with a pituitary tumor.
  • The patient is under 18 years old.

Take special care and check with your doctor before taking amisulpride if:

  • You have kidney problems.
  • You have diabetes. Your diabetes may need careful monitoring.
  • You have Parkinsonʼs disease.
  • You have ever had fits (epileptic seizures).
  • You have an unusual heart rate (rhythm).
  • You are elderly. This is because elderly people are more likely to get low blood pressure or feel sleepy.
  • You have low potassium levels in your blood.
  • You are taking any drugs which may lower potassium levels (such as thiazide, diuretics, bendroflumethiazide, hydrochlorothiazide).
  • You have been told by your doctor that you might have a stroke.
  • You or someone else in your family has a history of blood clots, as medicines like these have been associated with formation of blood clots.
  • You have a low number of white blood cells (agranulocytosis). This means you may get infections more easily than usual.
  • You have frequent infections such as fever, severe chills, sore throat or mouth ulcers. These could be signs of a blood problem called “leukopenia”.
  • You or someone else in your family has a history of breast cancer.
  • You have high levels of prolactin.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using amisulpride during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking amisulpride.

Side effects

What side effects can occur from amisulpride?

Stop taking amisulpride and see a doctor or go to a hospital straight away if:

  • You get swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty in swallowing or breathing. You could also notice an itchy, lumpy rash (hives) or nettle rash (urticaria). This may mean you are having an allergic reaction to amisulpride tablets.
  • You have an unusual heart rate, very fast heart rate or chest pain. These could be signs of a heart attack or life-threatening heart disorder.
  • You have a high temperature, sweating, stiff muscles, fast heartbeat, fast breathing and feel confused, drowsy or agitated. These could be the symptoms of a serious side effect called “neuroleptic malignant syndrome”.
  • You have a fit (seizure). This side effect happens in less than 1 in 100 people who take this medicine.
  • You have blood clots in the veins especially in the legs (symptoms include swelling, pain and redness in the leg), which may travel through blood vessels to the lungs causing chest pain and difficulty in breathing. If you notice any of these symptoms seek medical advice immediately.
  • You get more infections than usual. This could be because of a blood disorder (agranulocytosis) or a decrease in the number of white blood cells (neutropenia).

Tell your doctor as soon as possible if you have any of the following side effects:

  • Trembling, muscle stiffness or spasm, slow movement, producing more saliva than usual or feeling restless. (These symptoms can be reduced if your doctor lowers your dose of amisulpride or prescribes an additional medicine). This side effect affects more than 1 in 10 people taking amisulpride.
  • Movements that you cannot control, mainly of your arms and legs (this will usually be reduced if your dose of amisulpride is lowered by your doctor or if your doctor prescribes you an additional medicine). This side effect affects less than 1 in 10 people taking amisulpride.
  • Movements that you cannot control, mainly of your face or tongue. This side effect affects less than 1 in 100 people taking amisulpride.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with amisulpride?

Amisulpride may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Levodopa, a medicine to treat Parkinsonʼs disease
  • Drugs called “dopamine agonists” such as ropinirole and bromocriptine
  • Medicines used to control your heart beat such as quinidine, disopyramide, amiodarone and sotalol
  • Other anti-psychotic medicines used for mental problems
  • Medicines for high blood pressure and migraine such as clonidine, diltiazem and verapamil, guanfacine and digitalis
  • Mefloquine used to treat malaria
  • Medicines which help you sleep such as barbiturates and benzodiazepines
  • Pain-killers such as tramadol and indometacin
  • Anesthetics
  • Antihistamines such as promethazine which make you sleepy
  • Medicines that can affect the levels of sodium and potassium in your blood, such as water tablets, some laxatives, glucocorticoids, tetracosactide and amphotericin

Does food or alcohol interact with amisulpride?

Amisulpride may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with amisulpride?

Amisulpride may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using amisulpride.

What is the dose of amisulpride for an adult?

The usual dose is between 50mg and 800mg each day.

Your doctor may start you on a lower dose if necessary.

If necessary, your doctor can prescribe up to 1200mg each day.

Doses up to 300mg each day can be taken as a single dose. Take the dose at the same time each day.

Doses above 300mg should be taken half in the morning and half in the evening.

If you have kidney problems your doctor may prescribe you a lower dose.

Elderly people may be prescribed a lower dose. This is because amisulpride may make you feel sleepy or lower your blood pressure which could make you feel dizzy, light headed or faint.

What is the dose of amisulpride for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is amisulpride available?

Amisulpride is available in the following dosage forms and strengths:

  • Tablet 50mg, 100mg, 200mg and 400mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of amisulpride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: October 4, 2017 | Last Modified: September 13, 2019

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