What is Amiklin® (amikacin sulfate) used for?
Amiklin® is commonly used to prevent or treat a wide variety of bacterial infections such as meningitis (infection of the membranes that surround the brain and spinal cord) and infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary tract.
Amiklin® may be prescribed for other uses; ask your doctor or pharmacist for more information.
How should I take Amiklin® (amikacin sulfate)?
Amiklin® is given as an injection at your doctor’s office, hospital, or clinic. Contact your health care provider if you have any questions.
How do I store Amiklin® (amikacin sulfate)?
Amiklin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Amiklin® in the bathroom or the freezer. There may be different brands of Amiklin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Amiklin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Amiklin® (amikacin sulfate)?
Consult with your doctor or pharmacist, if:
- You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
- You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
- You have allergy with any of active or inactive ingredients of Amiklin® or other medications.
- You have any other illnesses, disorders, or medical conditions.
Is it safe during pregnancy or breastfeeding?
There are no adequate studies in women for determining risk when using Amiklin® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Amiklin®. Amiklin® is pregnancy risk category D, according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk
- B=No risk in some studies
- C=There may be some risk
- D=Positive evidence of risk
What side effects can occur from Amiklin® (amikacin sulfate)?
Amiklin® may cause following side effects, such as:
- Pain at the injection site
- Feeling sick
- Decreased appetite
Call your doctor immediately if you experience any of these symptoms:
- Peeling or blistering of the skin
- Swelling of the eyes, face, throat, tongue, or lips
- Difficulty breathing or swallowing
- Severe diarrhea (watery or bloody stools)
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Amiklin® (amikacin sulfate)?
Amiklin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Products may interact with this drug, including:
- Fluid tablets (e.g., frusemide, ethacrynic acid)
- Cisplatin, a medicine used to treat cancer
- Some other antibiotics (e.g., vancomycin, clindamycin, colistin, cephalosporin, penicillin)
- Amphotericin, a medicine used to treat some fungal infections
- Suxamethonium, a medicine used during surgery to relax muscles
- Some general anesthetic agents
- Opioid analgesics (e.g., codeine, morphine, pethidine, fentanyl)
Does food or alcohol interact with Amiklin® (amikacin sulfate)?
Amiklin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Amiklin® (amikacin sulfate)?
Amiklin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
These health conditions are:
- Kidney disease
- Eating disorders
- Cystic fibrosis (an inherited condition that affects the lungs and digestive system)
- Problems with your muscles such as myasthenia gravis or Parkinson’s disease
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.
What is the dose of Amiklin® (amikacin sulfate) for an adult?
The recommended dose is 15 mg/kg/day divided IV/IM q8-12hr.
Urinary Tract Infection:
The recommended dose is 250 mg IV/IM q12hr.
Extended Interval Dosing (q24 Hours)
- First dose: 15 mg/kg IV based on lean body weight.
- Subsequent doses: consult pharmacist.
Hospital Acquired Pneumonia:
The recommended dose is 20 mg/kg/day IV; may administer with antipseudomonal beta-lactam or carbapenem.
What is the dose of Amiklin® (amikacin sulfate) for a child?
The recommended dose is 15-22.5 mg/kg/day IV/IM divided 3 times a day.
Aged ≤7 days
- ≤29 weeks gestational age: The recommended dose is 18 mg/kg IV/IM every 48 hours.
- 30-33 weeks gestational age: The recommended dose is 18 mg/kg IV/IM every 36 hours.
- ≥34 weeks gestational age: The recommended dose is 15 mg/kg IV/IM every day.
Aged >7 days
- 30-33 weeks gestational age: The recommended dose is 15 mg/kg IV/IM every day.
- ≥34 weeks gestational age: The recommended dose is 15 mg/kg IV/IM every 12-18 hours.
Aged 8-28 days old & <29 weeks gestational age:
The recommended dose is 15 mg/kg IV/IM every 36 hours.
Neonates Aged >28 days old & <29 weeks gestational age:
The recommended dose is 15 mg/kg IV/IM every day.
How is Amiklin® (amikacin sulfate) available?
Amiklin® is available in the following dosage forms and strengths:
- Injectable Solution: 50mg/Ml
- Compounding Powder: 250mg
- Compounding Powder: 500mg
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Amiklin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Amikacin. http://reference.medscape.com/drug/amikin-amikacin-342516#0. Accessed January 05, 2017.
Amikacin. https://medlineplus.gov/druginfo/meds/a682661.html. Accessed January 05, 2017.
Amikacin. http://www.mims.com/singapore/drug/info/amikacin/?type=brief&mtype=generic. Accessed January 05, 2017.
Review Date: May 25, 2017 | Last Modified: September 12, 2019