Altretamine

By Medically reviewed by hellodoktor

Generic Name: Altretamine Brand Name(s): Generics only. No brands available.

Uses

What is altretamine used for?

Altretamine is commonly used for treating ovarian cancer. It may be given to you for other reasons. Talk with the doctor.

How should I take altretamine?

Use altretamine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take after meals and at bedtime.

How do I store altretamine?

Altretamine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store altretamine in the bathroom or the freezer. There may be different brands of altretamine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush altretamine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using altretamine?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of altretamine or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • You have any of these health problems: Bone marrow disease or nerve problems.
  • You are taking vitamin B6 (pyridoxine).

Tell all of your health care providers that you take altretamine. This includes your doctors, nurses, pharmacists, and dentists.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.

You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.

Talk with your doctor before getting any vaccines. Use with this medicine may either raise the chance of an infection or make the vaccine not work as well.

If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.

This medicine may cause harm to the unborn baby if you take it while you are pregnant.

Use birth control that you can trust to prevent pregnancy while taking altretamine.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using altretamine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking altretamine. Altretamine is pregnancy risk category D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from altretamine?

Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal
  • Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop
  • Very upset stomach or throwing up
  • Feeling very tired or weak
  • A burning, numbness, or tingling feeling that is not normal
  • Change in balance
  • Mood changes
  • Dizziness
  • Trouble walking
  • Upset stomach or throwing up

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with altretamine?

Altretamine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with altretamine?

Altretamine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with altretamine?

Altretamine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using altretamine.

What is the dose of altretamine for an adult?

Usual Adult Dose for Ovarian Cancer

260 mg/m2/day orally given in 4 divided doses after meals and at bedtime, either for 14 or 21 consecutive days in a 28-day cycle.

Use: Indicated as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent-based combination.

What is the dose of altretamine for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is altretamine available?

Altretamine is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of altretamine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: October 2, 2017 | Last Modified: September 12, 2019

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