Generic Name: Alprenolol Brand Name(s): Alprenolol.

Uses

What is alprenolol used for?

Alprenolol is commonly used in the treatment of cardiovascular diseases.

How should I take alprenolol?

Alprenolol is taken by mouth. Ask your doctor for more information.

How do I store alprenolol?

Alprenolol is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store alprenolol in the bathroom or the freezer. There may be different brands of alprenolol that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush alprenolol down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using alprenolol?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of alprenolol or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Alprenolol is contraindicated in case of:

  • 2nd and 3rd degree AV block
  • Sinus bradycardia
  • Uncontrolled heart failure
  • Asthma or bronchospasm
  • Severe peripheral arterial disease
  • Metabolic acidosis
  • Phaeochromocytoma
  • 1st degree AV block

Alprenolol may mask symptoms of hyperthyroidism and hypoglycaemia, may unmask myasthenia gravis, may aggravate psoriasis.

Abrupt withdrawal may cause angina, MI, ventricular arrhythmias and death.

Patients on long-term treatment should discontinue medication gradually over 1-2 week.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using alprenolol during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking alprenolol.

Side effects

What side effects can occur from alprenolol?

Side effects may occur when using this drug, such as:

  • Bradycardia
  • Heart failure, heart block
  • Hypotension
  • Bronchospasm
  • Fatigue
  • Coldness of extremities
  • Pneumonitis
  • Pulmonary and retroperitoneal fibrosis
  • Pleurisy
  • CNS effects
  • Myopathies
  • GI disturbances
  • Reversible alopoecia
  • Skin rash
  • Pruritus
  • Lupus-like syndrome
  • Male impotence
  • Sclerosing peritonitis
  • Muscle cramps
  • Paraesthesias
  • Peripheral neuropathy
  • Haematological reactions
  • Changes in blood concentrations of glucose, triglycerides and cholesterol

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with alprenolol?

Alprenolol may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Other drugs that cause hypotension
  • NSAIDs
  • Other cardiac depressants
  • Sotalol
  • Digoxin
  • Insulin and oral hypoglycaemics
  • Sympathomimetics
  • ACE inhibitors
  • Ca-channel blockers, verapamil
  • Anaesthetics causing myocardial depression (e.g. ether, cyclopropane, trichloroethylene)

Does food or alcohol interact with alprenolol?

Alprenolol may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with alprenolol?

Alprenolol may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using alprenolol.

What is the dose of alprenolol for an adult?

Adult: PO HTN 200 mg/day in divided doses, may increase weekly if needed. Angina pectoris; Cardiac arrhythmias 200-400 mg/day in divided doses.

What is the dose of alprenolol for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is alprenolol available?

Alprenolol is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of alprenolol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 29, 2017 | Last Modified: September 29, 2017

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