Generic Name: Aliskiren Brand Name(s): Aliskiren.

Uses

What is aliskiren used for?

Aliskiren is commonly used for treating high blood pressure. It may be given to you for other reasons. Talk with the doctor.

How should I take aliskiren?

Use aliskiren as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take with or without food. Always take with food or always take on an empty stomach.

Take this medicine at the same time of day.

To gain the most benefit, do not miss doses.

Keep taking aliskiren as you have been told by your doctor or other health care provider, even if you feel well.

Drink lots of non-caffeine liquids unless told to drink less liquid by your doctor.

How do I store aliskiren?

Aliskiren is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store aliskiren in the bathroom or the freezer. There may be different brands of aliskiren that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush aliskiren down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using aliskiren?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of aliskiren or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • You are taking any of these drugs: Cyclosporine or itraconazole.
  • You have high blood sugar (diabetes) or kidney disease and are taking certain drugs for high blood pressure or your heart. Talk with your doctor.

Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.

Avoid driving and doing other tasks or actions that call for you to be alert until you see how aliskiren affects you.

To lower the chance of feeling dizzy or passing out, rise slowly over a few minutes when sitting or lying down. Be careful climbing stairs.

Have your blood pressure checked often. Talk with your doctor.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

It may take 2 weeks to see the full effect.

If you are on a low-salt or salt-free diet, talk with your doctor.

If you are taking a salt substitute that has potassium, potassium-sparing diuretics, or potassium, talk with your doctor.

Talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.

Talk with your doctor before you drink alcohol.

Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.

Tell your doctor if you have too much sweat, fluid loss, throwing up, or loose stools. This may lead to low blood pressure.

If you are 65 or older, use this medicine with care. You could have more side effects.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using aliskiren during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking aliskiren. Aliskiren is pregnancy risk category D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from aliskiren?

Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain
  • Signs of a high potassium level like a heartbeat that does not feel normal; change in thinking clearly and with logic; feeling weak, lightheaded, or dizzy; feel like passing out; numbness or tingling; or shortness of breath
  • Signs of low sodium levels like headache, trouble focusing, memory problems, feeling confused, weakness, seizures, or change in balance
  • Very bad dizziness or passing out
  • Seizures
  • Belly pain
  • Throwing up
  • Trouble swallowing
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes
  • Dizziness
  • Cough
  • Loose stools (diarrhea)
  • Back pain
  • Flu-like signs
  • Headache
  • Feeling tired or weak

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with aliskiren?

Aliskiren may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with aliskiren?

Aliskiren may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with aliskiren?

Aliskiren may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using aliskiren.

What is the dose of aliskiren for an adult?

Usual Adult Dose for Hypertension

Initial: 150 mg orally once a day

Maintenance: the dosage may be increased to 300 mg daily if blood pressure is not adequately controlled.

What is the dose of aliskiren for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is aliskiren available?

Aliskiren is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Aliskiren, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 27, 2017 | Last Modified: September 27, 2017

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