Albumin

By Medically reviewed by hellodoktor

Generic Name: Albumin Brand Name(s): Albumin.

Know the basics

What is albumin used for?

Albumin (human) is a concentrate of plasma proteins from the human blood. It works by increasing plasma volume or serum albumin levels.

Albumin is commonly used for treating:

  • Shock because of blood loss in the body, burns, low protein levels due to surgery or liver failure, and as an additional medicine in bypass surgery;
  • Certain conditions which are determined by your doctor.

How should I take albumin?

Albumin is usually administered as an injection at your doctor’s office, hospital, or clinic. If you are using albumin at home, carefully follow the injection procedures by your health care provider.

How do I store albumin?

Albumin is stable for three years providing storage temperature does not exceed 30 °C. Protect from freezing. There may be different brands of albumin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush albumin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using albumin?

Consult with your doctor if:

  • You are allergic to any ingredient in albumin (human);
  • You have or have had heart failure, kidney failure or stable chronic anemia, or you are at risk for fluid overload;
  • You are pregnant, planning to become pregnant, or are breastfeeding;
  • You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement;
  • You have allergies to medicines, foods, or other substances.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using albumin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking albumin. Albumin is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Know the side effects

What side effects can occur from albumin?

  • Urticaria, skin rash, pruritus, edema, and erythema;
  • A headache, chills, and febrile reactions;
  • Hypotension;
  • Nausea, vomiting, and increased salivation;
  • Bronchospasm.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with albumin?

Albumin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with albumin?

Albumin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with albumin?

Albumin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

  • Decompensated cardiac insufficiency;
  • Hypertension Esophageal varices;
  • Pulmonary edema;
  • Hemorrhagic diathesis;
  • Severe anemia;
  • Renal and post-renal anuna.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using albumin.

What is the dose of albumin for an adult?

Usual dosing guidelines

  • Initial: 25 g (5% or 25% solution) IV infusion; may repeat q15-30min if response inadequate;
  • Not to exceed 250 g/48 hr.

25% Solution use for these health conditions

  • Acute nephritis;
  • Acute liver failure;
  • ARDS;
  • Burns;
  • Cardiopulmonary bypass;
  • Hypoproteinemia;
  • Renal dialysis;
  • Hypovolemic shock;
  • Hemolytic disease of newborn;
  • Hepatic surgery/transplantation.

5% Solution use for these health conditions

  • Hypovolemic shock;
  • Burns;
  • Hypoproteinemia;
  • Cardiopulmonary bypass;
  • Acute liver disease.

What is the dose of albumin for a child?

Usual dosing guidelines

  • Neonates (<28 days old)/infants: 10-20 mL/kg IV of 5% solution;500-1000 mg/kg IV infusion;
  • Not to exceed 250 g/48 hr or 6 g/kg/day.

How is albumin available?

Albumin is available in the following dosage forms and strengths:

  • Albumin human (intravenous solution) applies to the following strength(s): 5% ; 25% ; 20%.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of albumin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 24, 2016 | Last Modified: September 12, 2019

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