Adefovir

By

Generic Name: Adefovir Brand Name(s): Adefovir.

Uses

What is adefovir used for?

Adefovir is commonly used to treat hepatitis B infection.

How should I take adefovir?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take with or without food.

To gain the most benefit, do not miss doses.

Keep taking adefovir as you have been told by your doctor or other health care provider, even if you feel well.

How do I store adefovir?

Adefovir is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store adefovir in the bathroom or the freezer. There may be different brands of adefovir that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush adefovir down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using adefovir?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of adefovir or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

This medicine is not a cure for hepatitis infection. Stay under the care of your doctor.

This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.

This medicine is not approved for use in children younger than 12 years old. Talk with the doctor.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using adefovir during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking adefovir. Adefovir is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from adefovir?

Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes
  • Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain
  • Muscle pain or weakness
  • Bone pain
  • Headache
  • Loose stools (diarrhea)
  • Gas
  • Belly pain
  • Upset stomach or throwing up
  • Feeling tired or weak

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with adefovir?

Adefovir may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with adefovir?

Adefovir may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with adefovir?

Adefovir may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using adefovir.

 

What is the dose of adefovir for an adult?

Usual Adult Dose for Chronic Hepatitis B

10 mg orally once a day, without regard to food

What is the dose of adefovir for a child?

Usual Pediatric Dose for Chronic Hepatitis B

Less than 12 years: Not recommended.

12 years or older: 10 mg orally once a day, without regard to food

How is adefovir available?

Adefovir is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of adefovir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: September 14, 2017 | Last Modified: September 14, 2017

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