Aclarubicin

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Generic Name: Aclarubicin Brand Name(s): Generics only. No brands available.

Uses

What is aclarubicin used for?

Aclarubicin is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. It has a selective inhibitory effect on the synthesis of RNA in the cells.

How should I take aclarubicin?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

How do I store aclarubicin?

Aclarubicin is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store aclarubicin in the bathroom or the freezer. There may be different brands of aclarubicin that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush aclarubicin down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using aclarubicin?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of aclarubicin or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Caution should be exercised in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding.

Monitor complete blood counts, liver function, uric acid level in blood regularly while taking this medication.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using aclarubicin during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking aclarubicin. Aclarubicin is pregnancy risk category D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from aclarubicin?

Side effects may occur when using this drug, such as:

  • Severe Effects: Heart damage and bone marrow suppression
  • Gastrointestinal: Nausea, vomiting, irritant to tissue, sore mouth, diarrhea, and gastrointestinal tract inflammation
  • Blood: Anemia, bone-marrow suppression
  • Skin: Hair loss
  • Liver: Hepatic dysfunction
  • Genitourinary: Blood in urine

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with aclarubicin?

Aclarubicin may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with aclarubicin?

Aclarubicin may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with aclarubicin?

Aclarubicin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using aclarubicin.

What is the dose of aclarubicin for an adult?

Adult: IV- Initial: 175-300 mg/m2, divided over 3-7 consecutive days. Maintenance: 25-100 mg/m2 3-4 weekly.

What is the dose of aclarubicin for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information

How is aclarubicin available?

Aclarubicin is available in the following dosage forms and strengths:

  • Injection

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of aclarubicin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: September 13, 2017 | Last Modified: September 13, 2017

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