Acetohydroxamic acid


Generic Name: Acetohydroxamic acid Brand Name(s): Generics only. No brands available.


What is acetohydroxamic acid used for?

Acetohydroxamic acid is commonly used to lower the level of ammonia in your urine, which may help with some types of urinary infections.

How should I take acetohydroxamic acid?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take on an empty stomach. Take 1 hour before or 2 hours after meals.

Do not take iron, multivitamins, or other products that contain iron with acetohydroxamic acid.

To gain the most benefit, do not miss doses.

Keep taking this medicine as you have been told by your doctor or other health care provider, even if you feel well.

How do I store acetohydroxamic acid?

Acetohydroxamic acid is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store acetohydroxamic acid in the bathroom or the freezer. There may be different brands of acetohydroxamic acid that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush acetohydroxamic acid down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using acetohydroxamic acid?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of acetohydroxamic acid or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • You have a bladder infection that can be treated by other drugs or surgery.
  • You have kidney disease.

Tell all of your health care providers that you take acetohydroxamic acid. This includes your doctors, nurses, pharmacists, and dentists.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

Some people have had a rash with redness, warmth, and tingling after drinking alcohol while taking this medicine. The rash usually happens 30 to 45 minutes after drinking alcohol, and goes away within 30 to 60 minutes. Talk with your doctor before you drink alcohol with acetohydroxamic acid.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using acetohydroxamic acid during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking acetohydroxamic acid. Acetohydroxamic acid is pregnancy risk category X, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from acetohydroxamic acid?

Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat
  • Chest pain or pressure
  • Swelling, warmth, numbness, change of color, or pain in a leg or arm
  • A heartbeat that does not feel normal
  • Dark urine or yellow skin or eyes
  • Feeling very tired or weak
  • Very upset stomach or throwing up
  • Low mood (depression)
  • Headache
  • Feeling nervous and excitable
  • Anxiety
  • Feeling tired or weak
  • Upset stomach or throwing up
  • Not hungry
  • Shakiness
  • Hair loss

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with acetohydroxamic acid?

Acetohydroxamic acid may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with acetohydroxamic acid?

Acetohydroxamic acid may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with acetohydroxamic acid?

Acetohydroxamic acid may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using acetohydroxamic acid.

What is the dose of acetohydroxamic acid for an adult?

Usual Adult Dose for Urinary Tract Infection

Starting dose: 12 mg/kg/day administered at 6 to 8 hour intervals at a time when the stomach is empty.

Then progress to one tablet orally 3 to 4 times a day in a total daily dose of 10 to 15 mg/kg/day.

The maximum daily dose should be no more than 1.5 grams, regardless of body weight.

What is the dose of acetohydroxamic acid for a child?

Usual Pediatric Dose for Urinary Tract Infection

Children with chronic, recalcitrant, urea-splitting urinary infection may benefit from treatment with acetohydroxamic acid. However, detailed studies involving dosage and dose intervals in children have not been established.

Children have tolerated a dose of 10 mg/kg/day, taken in two or three divided doses, satisfactorily for periods up to one year. Therefore, an initial dose of 10 mg/kg/day orally is recommended.

Close monitoring of the patient’s clinical condition and hematologic status is recommended. Titration of the dose to higher or lower levels may be required to obtain an optimum therapeutic effect and/or to reduce the risk of side effects. 

How is acetohydroxamic acid available?

Acetohydroxamic acid is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of acetohydroxamic acid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: September 12, 2017 | Last Modified: September 12, 2017

You might also like