Generic Name: Acetaminophen-Caffeine-Isometheptene Mucate Brand Name(s): Generics only. No brands available. Avability: Rx, OTC Pregnancy Category: N

Uses

What is Acetaminophen-Caffeine-Isometheptene Mucate used for?

Acetaminophen-Caffeine-Isometheptene Mucate is a combination medication used to relieve tension and migraine headaches. Headache pain can sometimes be caused by widened blood vessels in the head. Isometheptene works by narrowing these widened blood vessels. Caffeine also works by narrowing widened blood vessels in the head, and is a mild stimulant. Acetaminophen relieves mild to moderate pain from various causes, including headache.

How should I take Acetaminophen-Caffeine-Isometheptene Mucate?

Take this medication by mouth with or without food as directed by your doctor. The dosage is based on your medical condition and response to treatment.

For migraine headache, take this medication at the first sign of a migraine as directed by your doctor, usually 1 to 2 tablets first, followed by 1 tablet every hour until the headache is relieved. Do not take more than 5 tablets in a 12-hour period.

For tension headache, take as directed by your doctor, usually every 4 hours as needed. Do not take more than 8 tablets in a 24-hour period.

Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

If you are using drugs for migraine attacks on 10 or more days each month, the drugs may actually make your headaches worse (medication overuse headache). Do not use medications more often or for longer than directed. Tell your doctor if you need to use this medication more often, or if the medication is not working as well, or if your headaches get worse.

How do I store Acetaminophen-Caffeine-Isometheptene Mucate?

Acetaminophen-Caffeine-Isometheptene Mucate is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Acetaminophen-Caffeine-Isometheptene Mucate in the bathroom or the freezer. There may be different brands of Acetaminophen-Caffeine-Isometheptene Mucate that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Acetaminophen-Caffeine-Isometheptene Mucate down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Acetaminophen-Caffeine-Isometheptene Mucate?

Before taking this medication, tell your doctor or pharmacist if you are allergic to isometheptene, acetaminophen, or caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (for example, in your legs, arms/hands), high blood pressure, glaucoma, heart problems (such as chest pain, previous heart attack), kidney disease, liver disease, stroke or “mini-stroke” (transient ischemic attack), use/abuse of alcohol.

Before having surgery or certain medical procedures (such as a heart stress test or a procedure to restore a normal heart rhythm if you have an unusually fast heartbeat), tell your doctor or dentist that you use this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Acetaminophen and caffeine pass into breast milk. It is unknown if isometheptene passes into breast milk. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Acetaminophen-Caffeine-Isometheptene Mucate during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Acetaminophen-Caffeine-Isometheptene Mucate. Acetaminophen-Caffeine-Isometheptene Mucate is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Acetaminophen-Caffeine-Isometheptene Mucate?

Dizziness, trouble sleeping, nervousness, or nausea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Acetaminophen-Caffeine-Isometheptene Mucate?

A product that may interact with this drug is: ketoconazole.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Do not take any MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.

This medication may interfere with certain medical/laboratory tests (including urine catecholamine/5-HIAA levels, dipyridamole-thallium imaging), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Acetaminophen-Caffeine-Isometheptene Mucate may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Acetaminophen-Caffeine-Isometheptene Mucate?

Acetaminophen-Caffeine-Isometheptene Mucate may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana.

What health conditions may interact with Acetaminophen-Caffeine-Isometheptene Mucate?

Acetaminophen-Caffeine-Isometheptene Mucate may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Acetaminophen-Caffeine-Isometheptene Mucate.

What is the dose of Acetaminophen-Caffeine-Isometheptene Mucate for an adult?

Usual Adult Dose for Headache

Migraine headache: 2 capsules or caplets at once orally, followed by one capsule or caplet every hour until relieved, up to 5 capsules or caplets within a 12 hour period

Tension headache: 1 to 2 capsules or caplets every 4 hours, up to 8 capsules or caplets a day

Renal Dose Adjustments

Severe renal impairment: Contraindicated

Liver Dose Adjustments

Hepatic disease: Contraindicated

What is the dose of Acetaminophen-Caffeine-Isometheptene Mucate for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Acetaminophen-Caffeine-Isometheptene Mucate available?

Acetaminophen-Caffeine-Isometheptene Mucate is available in the following dosage forms and strengths:

  • Oral tablet,
  • Oral capsule.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Acetaminophen-Caffeine-Isometheptene Mucate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

 

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: November 6, 2018 | Last Modified: November 6, 2018

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