Generic Name: Abaloparatide Brand Name(s): Generics only. No brands available. Avability: Rx Pregnancy Category: N

Uses

What is Abaloparatide used for?

Abaloparatide is used to treat bone loss (osteoporosis) for women after menopause who are at high risk of having broken bones (fractures). It is similar to a natural hormone in your body (parathyroid hormone). It works by increasing bone density and strength. This effect helps to decrease the risk of having a fracture.

This medication should not be used for children or young adults whose bones are still growing.

How should I take Abaloparatide?

If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin.

Inject this medication under the skin of the abdomen area as directed by your doctor, usually once daily. When you give the first several doses, make sure you are in a place where you can sit or lie down if you have dizziness.

Learn how to store and discard medical supplies safely.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

How do I store Abaloparatide?

Store unopened injection pens in the refrigerator, do not freeze. Once you start using the injection pen, store it at room temperature away from moisture and heat. After each use, remove the needle and cover the pen with the outer needle cap. Do not store the pen with a needle attached.

Each prefilled injection pen contains enough abaloparatide for 30 separate injections. Throw the pen away after 30 injections, even if there is still medicine left inside.

There may be different brands of Abaloparatide that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Abaloparatide down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Abaloparatide?

Before using abaloparatide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other bone disorders (such as bone cancer), high level of calcium in the blood, kidney stones, kidney disease, high level of parathyroid hormone.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication is not usually used in women of childbearing age. It is unlikely to be used during pregnancy or breast-feeding. Consult your doctor if you have any questions about this medication.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Abaloparatide during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Abaloparatide. Abaloparatide is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Abaloparatide?

Dizziness or fast heartbeat may occur within 4 hours after using this medication. If these effects occur, sit or lie down right away. These symptoms usually go away within a few hours. These effects should go away after several doses as your body adjusts to the medication. Redness/pain/swelling at the injection site may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: signs of a high level of calcium in the blood (such as nausea, vomiting, constipation, unusual tiredness, muscle weakness, mental/mood changes including confusion).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Abaloparatide?

Abaloparatide may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Abaloparatide?

Abaloparatide may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana.

What health conditions may interact with Abaloparatide?

Abaloparatide may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Abaloparatide.

What is the dose of Abaloparatide for an adult?

Usual Adult Dose for Osteoporosis

80 mcg subcutaneously once a day

Comments:

-Cumulative use of this drug and parathyroid hormone analogs (e.g., teriparatide) for more than 2 years during a patient’s lifetime is not recommended.

-Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate.

Use: For the treatment of postmenopausal women with osteoporosis at high risk for fracture defined as a history of osteoporotic fracture, multiple risk factors for fracture, or patients who have failed or are intolerant to other available osteoporosis therapy; in postmenopausal women with osteoporosis, this drug reduces the risk of vertebral fractures and nonvertebral fractures

Renal Dose Adjustments

No adjustment recommended.

What is the dose of Abaloparatide for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Abaloparatide available?

Abaloparatide is available in the following dosage forms and strengths:

  • Subcutaneous solution.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Abaloparatide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

 

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: November 5, 2018 | Last Modified: November 5, 2018

Want to live your best life?
Get the Hello Doktor Daily newsletter for health tips, wellness updates and more.