Generic Name: Apo Ranitidine Brand Name(s): Generics only. No brands available.

Uses

What is apo ranitidine used for?

Apo ranitidine is commonly used to treat ulcers of the stomach, intestines and prevent them from coming back after they have healed. It is also used to treat certain stomach and throat (esophagus) problems such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome.

It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn’t go away, stomach pain, heartburn, and difficulty swallowing.

Apo ranitidine may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take apo ranitidine?

Do not crush, break, or chew the tablets/capsules. Swallow apo ranitidine whole with a glass of water.

Ask your health care provider any questions you may have about how to use apo ranitidine.

How do I store apo ranitidine?

Apo ranitidine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store apo ranitidine in the bathroom or the freezer. There may be different brands of apo ranitidine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush apo ranitidine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using apo ranitidine?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of apo ranitidine or other medications.
  • You have any other illnesses, disorders, or medical conditions, such as stomach or bowel problems, liver problems or unexplained abnormal liver function tests, or kidney problems.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

Is it safe during pregnancy or breastfeeding?

Pregnancy:

There are no adequate studies in women for determining risk when using apo ranitidine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking apo ranitidine. Apo ranitidine is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Breastfeeding:

Drug crosses into breast milk; discontinue drug, use caution.

Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding.

Side effects

What side effects can occur from apo ranitidine?

Here are side effects:

  • Headache
  • Constipation
  • Diarrhea
  • Pain, redness, burning, or stinging
  • Vision changes
  • Nervousness
  • Confusion
  • Depression
  • Hallucinations
  • Easy bleeding/bruising
  • Enlarged breasts
  • Severe tiredness
  • Fast/slow/irregular heartbeat
  • Signs of infection (such as sore throat that doesn’t go away, fever, chills)
  • Severe abdominal/stomach pain
  • Dark urine
  • Yellowing eyes/skin
  • A sign of allergic reaction

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with apo ranitidine?

Apo Ranitidine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug including:

  • Taking atazanavir, dasatinib, delavirdine, certain azole antifungals (such as itraconazole, ketoconazole), pazopanib with apo ranitidine may affect the absorption of them.
  • Taking procainamide with apo ranitidine may increase the side effects of procainamide.
  • Takning warfarin with apo ranitidine may increase the risk of bleeding or blood clots.
  • Taking either midazolam or triazolam with apo ranitidine may increase the risk of extreme drowsiness.
  • Taking glipizide with apo ranitidine may increase the risk of low blood sugar.

Does food or alcohol interact with apo ranitidine?

Apo ranitidine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with apo ranitidine?

Apo ranitidine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, such as:

  • A certain blood disorder (porphyria)
  • Heart problems (such as irregular heartbeat)
  • Immune system problems
  • Kidneyproblems
  • Liver problems
  • Lung problems (such as asthma, chronic obstructive pulmonary disease-COPD)
  • Stomach problems (such as tumors)

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using apo ranitidine.

What is the dose of apo ranitidine for an adult?

Usual adult dose for duodenal ulcer

Oral: 150 mg 2 times a day, or 300 mg once a day after the evening meal or at bedtime.

Usual adult dose for dyspepsia

  • 75 mg orally once daily (Over-the-counter) 30 to 60 minutes before meal.
  • Dose may be increased to 75 mg twice daily.
  • Maximum duration of therapy if self-medicating is 14 days.

Usual adult dose for duodenal ulcer prophylaxis

150 mg orally once a day at bedtime.

Usual adult dose for gastric ulcer maintenance

150 mg orally once a day at bedtime.

Usual adult dose for erosive esophagitis

  • Initial: 150 mg 4 times a day.
  • Maintenance: 150 mg twice daily.

Usual adult dose for surgical prophylaxis

150 mg orally 2 hours before surgery.

Usual adult dose for Zollinger-Ellison syndrome

150 mg 2 times a day initially. Adjust dose to control gastric acid secretion.

Doses up to 6 g per day have been used.
Usual adult dose for pathological hypersecretory conditions

150 mg 2 times a day initially. Adjust dose to control gastric acid secretion.

Doses up to 6 g per day have been used.

Usual adult dose for gastroesophageal reflux disease

Oral: 150 mg twice daily.

Usual adult dose for gastric ulcer

Oral: 150 mg twice a day.

What is the dose of Apo Ranitidine for a child?

Usual pediatric dose for duodenal ulcer

1 month to 16 years:

  • Treatment: 4 to 8 mg/kg twice daily, every 12 hours; Maximum: 300 mg/day orally
  • Maintenance: 2 to 4 mg/kg/day orally once daily; Maximum: 150 mg/day orally

Usual pediatric dose for gastric ulcer

1 month to 16 years:

  • Treatment: 4 to 8 mg/kg twice daily, every 12 hours; Maximum: 300 mg/day orally.
  • Maintenance: 2 to 4 mg/kg/day orally once daily; Maximum: 150 mg/day orally.

Usual pediatric dose for duodenal ulcer prophylaxis

1 month to 16 years: 2 to 4 mg/kg once daily, not to exceed 150 mg/24 hours.

Usual pediatric dose for gastric ulcer maintenance

1 month to 16 years: 2 to 4 mg/kg once daily, not to exceed 150 mg/24 hours.

Usual pediatric dose for gastroesophageal reflux disease

Neonatal: 2 mg/kg/day divided into 2 doses, administered every 12 hours.
1 month to 16 years: 4 to 10 mg/kg/day administered in 2 divided doses, every 12 hours; Maximum: 300 mg orally day.

Usual pediatric dose for erosive esophagitis

1 month to 16 years: 4 to 10 mg/kg/day administered in 2 divided doses, every 12 hours; Maximum: 300 mg orally day.

Usual pediatric dose for dyspepsia

Children greater than or equal to 12 years: 75 mg orally once 30 to 60 minutes before eating food or drinking beverages which cause heartburn; Maximum: 150 mg/24 hours; Duration of therapy: Do not use for more than 14 days.

How is apo ranitidine available?

Apo ranitidine is available in the following dosage forms and strengths:

  • Apo ranitidine tablet 150mg
  • Apo ranitidine capsule 300mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

It is also important to carry a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking with you in case of emergencies.

What should I do if I miss a dose?

If you miss a dose of apo ranitidine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 4, 2017 | Last Modified: January 4, 2017

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