Generic Name: Axid Brand Name(s): Generics only. No brands available.


What is axid used for?

Axid is commonly used to treat ulcers of the stomach, intestines and prevent them from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems such as erosive esophagitis, gastroesophageal reflux disease-GERD.

Axid works by decreasing the amount of axid your stomach makes. It relieves symptoms such as cough that doesn’t go away, stomach pain, heartburn, and difficulty swallowing.

Axid may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take axid?

Take this medication by mouth with or without food as directed by your doctor, usually once or twice a day. If you are taking this medication once daily, it is usually taken right before bedtime.

Ask your health care provider any questions you may have about how to use axid.

How do I store axid?

Axid is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store axid in the bathroom or the freezer. There may be different brands of axid that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush axid down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using axid?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of axid or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

Is it safe during pregnancy or breastfeeding?


There are no adequate studies in women for determining risk when using axid during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking axid. Axid is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown


This drug crosses into breast milk.

Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding.

Side effects

What side effects can occur from axid?

Here are side effects may occur:

  • Headache
  • Diarrhea
  • Nausea
  • Vomiting
  • Loss of appetite
  • Stomach/abdominal pain
  • Yellowing eyes/skin
  • Dark urine
  • Confusion
  • Breast swelling/soreness in males
  • Easy bruising/bleeding
  • Signs of infection (such as sore throat that doesn’t go away, fever, chills)
  • Fast/pounding heartbeat
  • Unusual tiredness

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.



What drugs may interact with axid?

Axid may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

These are some interactions when taking axid with other medications:

  • Some products need stomach axid so that the body can absorb them properly. Nizatidine decreases stomach axid, so it may change how well these products work. Some affected products include atazanavir, dasatinib, delavirdine, certain azole antifungals (such as itraconazole, ketoconazole), pazopanib, among others.
  • Do not take this medication with other products that contain nizatidine or other H2 blockers (cimetidine, famotidine, ranitidine).
  • This medication may interfere with certain laboratory tests (including certain urine protein tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Does food or alcohol interact with axid?

Axid may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with axid?

Axid may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Immune system problems
  • Kidney problems
  • Liver problems
  • Certain lung diseases (such as chronic obstructive pulmonary disease-COPD)
  • Other stomach problems (such as tumors)


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of axid for an adult?

Active duodenal ulcer 

  • The recommended oral dosage for adults is 300 mg once daily at bedtime.
  • An alternative dosage regimen is 150 mg twice daily.

Maintenance of healed duodenal ulcer:

The recommended oral dosage for adults is 150 mg once daily at bedtime.

Gastroesophageal reflux disease:

The recommended oral dosage in adults for the treatment of erosions, ulcerations, and associated heartburn is 150mg twice daily.

Active benign gastric ulcer:

  • The recommended oral dosage is 300 mg given either as 150 mg twice daily or 300 mg once daily at bedtime.
  • Prior to treatment, care should be taken to exclude the possibility of malignant gastric ulceration.

What is the dose of axid for a child?

Gastroesophageal reflux disease:

5-10 mg/kg/day orally divided every 12hour (limited data).

How is axid available?

Axid is available in the following dosage forms and strengths:

  • Axid capsule: 150mg Nizatidine

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

It is also important to carry a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking with you in case of emergencies.

What should I do if I miss a dose?

If you miss a dose of axid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.


Review Date: December 29, 2016 | Last Modified: January 4, 2017

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