Generic Name: Typhim Vi Brand Name(s): Generics only. No brands available.

Uses

What is Typhim Vi vaccine used for?

Typhim Vi vaccine is commonly used for active immunization against typhoid fever caused by Salmonella enterica serovar typhi, in adults and children 2 years of age or older.

Typhim Vi vaccine may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take Typhim Vi vaccine?

  • Typhim Vi vaccine is given as an injection at your doctor’s office, hospital, or clinic.
  • For intramuscular use only, do not inject intravenously.
  • This vaccine should be given at least 2 weeks before being exposed to typhoid fever.
  • If Typhim Vi vaccine contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use.

Ask your health care provider any questions you may have about how to use Typhim Vi vaccine.

How do I store Typhim Vi vaccine?

Typhim Vi vaccine is best stored in the refrigerator. To prevent drug damage, do not freeze. There may be different brands of Typhim Vi vaccine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Typhim Vi vaccine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

 

Precautions & warnings

What should I know before using Typhim Vi vaccine?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Typhim Vi vaccine or other medications.
  • You have any other illnesses, disorders, or medical conditions, such as: stomach or bowel problems, liver problems or unexplained abnormal liver function tests, or kidney problems
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

Is it safe during pregnancy or breastfeeding?

Pregnancy:

There are no adequate studies in women for determining risk when using Typhim Vi vaccine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Typhim Vi vaccine. Typhim Vi vaccine is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Breastfeeding:

Not known if crosses into breast milk, using in nursing women with caution.

Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding.

Side effects

What side effects can occur from Typhim Vi vaccine?

Here are side effects:

  • General body discomfort
  • Headache
  • Muscle pain
  • Nausea
  • Tenderness, pain, redness, swelling, and hardening at the injection site
  • Weakness
  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Fainting
  • Severe or persistent dizziness

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Typhim Vi vaccine?

Typhim Vi vaccine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Typhim Vi vaccine may interact with suppress the immune system (e.g., certain cancer medicines, corticosteroids such as methylprednisolone, cyclosporine).

Does food or alcohol interact with Typhim Vi vaccine?

Typhim Vi vaccine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Typhim Vi vaccine?

Typhim Vi vaccine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, such as:

  • Weakened immune system or are unable to make antibodies due to HIV infection, cancer, or cancer therapy (e.g., chemotherapy or radiation).

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Typhim Vi vaccine for an adult?

The immunizing dose for adults is a single injection of 0.5 ml.

The dose for adults is typically given intramuscularly in the deltoid. The vaccine should not be injected into the gluteal area or areas where there may be a nerve trunk.

A reimmunizing dose is 0.5 ml. Reimmunization consisting of a single dose for US travelers every two years under conditions of repeated or continued exposure to the S typhi organism is recommended at this time.

What is the dose of Typhim Vi vaccine for a child?

The immunizing dose for children over 2 years is a single injection of 0.5 ml. The dose for children is given IM either in the deltoid or the anterolateral thigh. The vaccine should not be injected into the gluteal area or areas where there may be a nerve trunk.

A reimmunizing dose is 0.5 ml. Reimmunization consisting of a single dose for US travelers every two years under conditions of repeated or continued exposure to the S typhi organism is recommended at this time.

Children under 2 years of age: as with other polysaccharide vaccines, the antibody response may be inadequate in children under 2 years of age.

How is Typhim Vi vaccine available?

Typhim Vi vaccine is available in the following dosage forms and strengths:

  • Solution for Injection; each dose of 0.5 ml contains: 25mcg Typhoid Polysaccharide vaccine.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

It is also important to carry a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking with you in case of emergencies.

What should I do if I miss a dose?

If you miss a dose of Typhim Vi vaccine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 4, 2017 | Last Modified: January 4, 2017