Calcium chloride


Generic Name: Calcium chloride Brand Name(s): Generics only. No brands available.


What is calcium chloride used for?

Calcium chloride is commonly used for the immediate treatment of hypocalcemic tetany. Other therapy, such as parathyroid hormone or vitamin D, may be indicated according to the etiology of the tetany.

In cardiac resuscitation, particularly after open heart surgery, calcium chloride has been used when epinephrine has failed to improve weak or ineffective myocardial contractions.

Calcium chloride may be prescribed for other uses. Ask your doctor or pharmacist for more information.

How should I take calcium chloride?

Calcium chloride will be given by doctor.  Ask your health care provider any questions you may have about how to use medication.

How do I store calcium chloride?

Calcium chloride is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store calcium chloride in the bathroom or the freezer. There may be different brands of calcium chloride that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush calcium chloride down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using calcium chloride?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of calcium chloride or other medications.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using calcium chloride during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This calcium chloride is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.


As a component of human milk calcium enters milk. Use caution.

Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding.

Side effects

What side effects can occur from calcium chloride?

Calcium chloride may cause these side effects, such as:

  • Allergic reaction: rash, itching, difficulty in breathing or swelling of the face, lips, throat or tongue.
  • Nausea, abdominal pain, diarrhea, constipation, wind, skin rashes and itching, high concentration of calcium in the blood (hyper-calcaemia) or urine (hypercalciuria).

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.


What drugs may interact with calcium chloride?

Calcium chloride may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Calcium chloride may cause interactions with these medications:

  • Vitamin D;
  • Heart medicines such as digoxin and cardiac glycosides;
  • Tetracycline antibiotics;
  • Thiazide diuretics (water tablets);
  • Bisphosphonates and sodium fluoride (drugs used to treat bone disorders).

Does food or alcohol interact with calcium chloride?

Calcium chloride may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with calcium chloride?

Calcium chloride may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • An overactive parathyroid gland (hyperparathyroidism) or too much vitamin D in your body (hypervitaminosis D).
  • High levels of calcium in your blood, very high levels of calcium in your urine, kidney stones, or have severe kidney problems.
  • Galactosaemia (a rare genetic disorder which means you cannot metabolise the sugar galactose).


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of calcium chloride for an adult?

Hypocalcemia, emergency treatment

500-1000 mg Intravenous route over 5-10 minutes; may repeat as necessary.

Arrhythmias, emergent

Indicated for arrhythmias associated with hypocalcemia, hyperkalemia, or hypermagnesemia.

500-1000 mg intravenous route over 5-10 minutes.


500-1000 mg intravenous route over 2-5 minutes; observe the patient for signs of recovery; may repeat if CNS depression persists.

Calcium channel blocker overdose

1-2 g intravenous infused over 10-20 min; may repeat every 20 minutes when in need up to 5 doses.

Beta-blocker overdose, refractory to glucagon & high dose vasopressor

1000 mg intravenous bolus via central line.

Other information

1 g (10 ml) vials of calcium chloride 10% solution contain 273 mg (13.6 mEq) elemental calcium.

What is the dose of calcium chloride for a child?

Hypocalcemia, emergency treatment

  • Infants: <75 mg (20 mg elemental Ca) intravenous route; may repeat as necessary.
  • Children: 75-519 mg (20-140 mg elemental Ca) intravenous route, may repeat as necessary.

Hypocalcemic tetany

  • Neonates: 171 mg/kg/day intravenous injection in divided doses.
  • Infants and children: 10 mg/kg intravenous injection over 5-10 min 3-4 times a day; alternatively, may administer 35-50 mg/kg Intravenous injection 3-4 times a day.

How is calcium chloride available?

Calcium chloride is available in the following dosage forms and strengths:

  • Calcium chloride 100 mg/ml (10 %)solution.
  • Calcium chloride 100 mg/ml (10 %)syringe.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

It is also important to carry a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking with you in case of emergencies.

What should I do if I miss a dose?

If you miss a dose of medication, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: November 25, 2016 | Last Modified: January 4, 2017

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