What is patent foramen ovale?
Patent foramen ovale (PFO) is a hole between the left and right atria (upper chambers) of the heart. This hole exists in everyone before birth, but most often closes shortly after being born. PFO is what the hole is called when it fails to close naturally after a baby is born.
How common is patent foramen ovale?
Patent foramen ovale occurs in about 25 percent of the normal population, but most people with the condition never know they have it. Please discuss with your doctor for further information.
What are the symptoms of patent foramen ovale?
Most people with a patent foramen ovale don’t know they have it, because it’s usually a hidden condition that doesn’t create signs or symptoms.
There may be some symptoms not listed above. If you have any concerns about a symptom, please consult your doctor.
When should I see my doctor?
If you have any signs or symptoms listed above or have any questions, please consult with your doctor. Everyone’s body acts differently. It is always best to discuss with your doctor what is best for your situation.
What causes patent foramen ovale?
The opening is supposed to close soon after birth, but sometimes it does not. In about 1 out of 4 people, the opening never closes. If it does not close, it is called a PFO. The cause of a PFO is unknown.
What increases my risk for patent foramen ovale?
There are no known risk factors.
Diagnosis & treatment
The information provided is not a substitute for any medical advice. ALWAYS consult with your doctor for more information.
How is patent foramen ovale diagnosed?
A doctor trained in heart conditions (cardiologist) may order one or more of the following tests to diagnose a patent foramen ovale:
An echocardiogram shows the anatomy, structure and function of your heart.
A common type of echocardiogram is called a transthoracic echocardiogram. In this test, sound waves directed at your heart from a wandlike device (transducer) held on your chest produce video images of your heart in motion. Doctors may use this test to diagnose a patent foramen ovale and detect other heart problems.
Variations of this procedure may be used to identify patent foramen ovale, including:
Color flow Doppler. When sound waves bounce off blood cells moving through your heart, they change pitch. These characteristic changes (Doppler signals) and computerized colorization of these signals can help your doctor examine the speed and direction of blood flow in your heart. If you have a patent foramen ovale, a color flow Doppler echocardiogram could detect the flow of blood between the right atrium and left atrium.
Saline contrast study (bubble study). With this approach, a sterile salt solution is shaken until tiny bubbles form and then is injected into a vein. The bubbles travel to the right side of your heart and appear on the echocardiogram. If there’s no hole between the left atrium and right atrium, the bubbles will simply be filtered out in the lungs. If you have a patent foramen ovale, some bubbles will appear on the left side of the heart. The presence of a patent foramen ovale may be difficult to confirm by a transthoracic echocardiogram.
Doctors may conduct another type of echocardiogram called a transesophageal echocardiogram to get a closer look at the heart and blood flow through the heart. In this test, a small transducer attached to the end of a tube is inserted down the tube leading from your mouth to your stomach (esophagus).
This is generally the most accurate available test for doctors to see a patent foramen ovale by using the ultrasound in combination with color flow Doppler or a saline contrast study.
Your doctor may recommend additional tests if you’re diagnosed with a patent foramen ovale and you have had a stroke. Your doctor may also refer you to a doctor trained in brain and nervous system conditions (neurologist).
How is patent foramen ovale treated?
Most people with a patent foramen ovale don’t need treatment. In certain circumstances, however, your doctor may recommend that you or your child have a procedure to close the patent foramen ovale.
Reasons for closure
If a patent foramen ovale is found when an echocardiogram is done for other reasons, a procedure to close the opening usually isn’t performed. Procedures to close the patent foramen ovale may be done in certain circumstances, such as to treat low blood oxygen levels linked to the patent foramen ovale.
Closure of a patent foramen ovale to prevent migraines isn’t currently recommended. Closure of a patent foramen ovale to prevent a stroke remains controversial.
In some cases, doctors may recommend closure of the patent foramen ovale in individuals who have had recurrent strokes despite medical therapy, when no other cause has been found.
Surgical and other procedures for closure
Procedures to close a patent foramen ovale include:
- Device closure. Using cardiac catheterization, doctors can insert a device that plugs the patent foramen ovale. In this procedure, the device is on the end of a long flexible tube (catheter). The doctor inserts the device-tipped catheter into a vein in the groin and guides the device into place with the imaging assistance of an echocardiogram. Although complications are uncommon with this procedure, a tear of the heart or blood vessels, dislodgement of the device, or the development of irregular heartbeats may occur.
- Surgical repair. A surgeon can close the patent foramen ovale by opening up the heart and stitching shut the flap-like opening. This procedure can be conducted using a very small incision and may be performed using robotic techniques. If you or your child is undergoing surgery to correct another heart problem, your doctor may recommend that you have the patent foramen ovale corrected surgically at the same time. Research is ongoing to determine the benefits of closing the patent foramen ovale during heart surgery to correct another problem.
Medications can be used to try to reduce the risk of blood clots crossing a patent foramen ovale. Antiplatelet therapy such as aspirin or clopidogrel (Plavix) and other blood thinning medications (anticoagulants) — such as warfarin (Coumadin, Jantoven), dabigatran (Pradaxa), apixaban (Eliquis) and rivaroxaban (Xarelto) — may be helpful for people with a patent foramen ovale who’ve had a stroke.
It’s not clear whether medications or procedures to close the defect are most appropriate for stroke prevention in people with a patent foramen ovale. Studies are ongoing to answer this question.
Lifestyle changes & home remedies
What are some lifestyle changes or home remedies that can help me manage patent foramen ovale?
The following lifestyles and home remedies might help you cope with patent foramen ovale:
- If you know you have a patent foramen ovale, but don’t have symptoms, you probably won’t have any restrictions on your activities.
- If you’ll be traveling long distances, it’s important to follow recommendations for preventing blood clots. If you’re traveling by car, stop periodically and go for a short walk. On an airplane, be sure to stay well-hydrated and walk around whenever it’s safe to do so.
If you have any questions, please consult with your doctor to better understand the best solution for you.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Patent foramen ovale. https://www.mayoclinic.org/diseases-conditions/patent-foramen-ovale/symptoms-causes/syc-20353487. Accessed November 27, 2017.
Patent foramen ovale. https://medlineplus.gov/ency/article/001113.htm. Accessed November 27, 2017.
Patent Foramen Ovale (PFO). https://my.clevelandclinic.org/health/articles/patent-foramen-ovale. Accessed November 27, 2017.
Review Date: November 27, 2017 | Last Modified: November 28, 2017