What is hypertrophic cardiomyopathy?
Hypertrophic cardiomyopathy (HCM) is a disease in which the heart muscle (myocardium) becomes abnormally thick (hypertrophied). The thickened heart muscle can make it harder for the heart to pump blood.
Hypertrophic cardiomyopathy often goes undiagnosed because many people with the disease have few, if any, symptoms and can lead normal lives with no significant problems. However, in a small number of people with HCM, the thickened heart muscle can cause shortness of breath, chest pain or problems in the heart’s electrical system, resulting in life-threatening abnormal heart rhythms (arrhythmias).
How common is hypertrophic cardiomyopathy?
Hypertrophic cardiomyopathy is extremely common. It can affect patients at any age. It can be managed by reducing your risk factors. Please discuss with your doctor for further information.
What are the symptoms of hypertrophic cardiomyopathy?
- The common Shortness of breath, especially during exercise
- Chest pain, especially during exercise
- Fainting, especially during or just after exercise or exertion
- Sensation of rapid, fluttering or pounding heartbeats (palpitations)
- Heart murmur, which a doctor might detect while listening to your heart
There may be some symptoms not listed above. If you have any concerns about a symptom, please consult your doctor.
When should I see my doctor?
If you have any signs or symptoms listed above or have any questions, please consult with your doctor. Everyone’s body acts differently. It is always best to discuss with your doctor what is best for your situation.
A number of conditions can cause shortness of breath and heart palpitations. It’s important to get a prompt, accurate diagnosis and appropriate care. See your doctor if you experience any symptoms associated with hypertrophic cardiomyopathy.
Seek emergency care if you experience any of the following symptoms for more than a few minutes:
- Rapid or irregular heartbeat
- Difficulty breathing
- Chest pain
What causes hypertrophic cardiomyopathy?
Hypertrophic cardiomyopathy is usually caused by abnormal genes (gene mutations) that cause the heart muscle to grow abnormally thick. People with hypertrophic cardiomyopathy also have an abnormal arrangement of heart muscle cells, a condition known as myofiber disarray. This disarray can contribute to arrhythmia in some people.
The severity of hypertrophic cardiomyopathy varies widely. Most people with hypertrophic cardiomyopathy have a form of the disease in which the wall (septum) between the two bottom chambers of the heart (ventricles) becomes enlarged and impedes blood flow out of the heart. This condition is sometimes called obstructive hypertrophic cardiomyopathy.
Sometimes hypertrophic cardiomyopathy occurs without significant blocking of blood flow. However, the heart’s main pumping chamber (left ventricle) may become stiff, reducing the amount of blood the ventricle can hold and the amount pumped out to the body with each heartbeat. This condition is sometimes called non-obstructive hypertrophic cardiomyopathy.
What increases my risk for hypertrophic cardiomyopathy?
Hypertrophic cardiomyopathy is usually inherited. There’s a 50 percent chance that the children of a parent with hypertrophic cardiomyopathy will inherit the genetic mutation for the disease. Close relatives — parents, children or siblings — of a person with hypertrophic cardiomyopathy should ask their doctors about screening for the disease.
Diagnosis & treatment
The information provided is not a substitute for any medical advice. ALWAYS consult with your doctor for more information.
How is hypertrophic cardiomyopathy diagnosed?
Your doctor may review your medical and family history, discuss your signs and symptoms, and conduct a physical examination. Your doctor may order several tests to diagnose hypertrophic cardiomyopathy (HCM).
Your doctor is likely to recommend an imaging test called an echocardiogram to diagnose hypertrophic cardiomyopathy. This test allows your doctor to see whether your heart muscle is abnormally thick, your blood flow is obstructed and your heart valves are moving normally.
Types of echocardiography include:
- Transthoracic echocardiogram. In this test, a device (transducer) is pressed firmly against your skin. The transducer aims an ultrasound beam through your chest to your heart, producing moving images of the working of the heart.
- Transesophageal echocardiogram. In a transesophageal echocardiogram, doctors guide a flexible tube containing a transducer down your throat and into the tube connecting your mouth and stomach (esophagus). From there, the transducer can obtain more-detailed images of your heart. This test may be recommended if it’s difficult to get a clear picture of your heart with a standard echocardiogram or if the doctor wants to further examine your mitral valve. This test is done in very few people with hypertrophic cardiomyopathy.
Additional tests might be ordered to look for other effects of hypertrophic cardiomyopathy and help your doctor determine the most appropriate treatment for your condition. These additional tests include:
- Electrocardiogram (ECG). Wires (electrodes) attached to adhesive pads on your skin measure electrical impulses from your heart. An ECG can detect enlarged chambers of your heart and abnormal heart rhythms.
- Treadmill stress test. Your heart rhythm, blood pressure and breathing are monitored while you walk on a treadmill. Your doctor may recommend a treadmill stress test to evaluate symptoms, determine your exercise capacity, and determine if exercise provokes abnormal heart rhythms. Treadmill stress tests are sometimes performed with echocardiography if you have symptoms of HCM but a resting echocardiogram doesn’t show obstructed blood flow. This test is commonly used in people with hypertrophic cardiomyopathy.
- Holter monitor. You may wear a portable ECG that records your heart’s activity continuously over one to two days. This test is often done in people with hypertrophic cardiomyopathy.
- Cardiac MRI. A cardiac MRI uses magnetic fields and radio waves to create images of your heart. Cardiac MRI is often used in addition to echocardiography in the evaluation of people with hypertrophic cardiomyopathy.
- Cardiac catheterization. In this procedure, a catheter is inserted into a blood vessel, usually in your neck or groin area. The catheter is then carefully threaded to your heart chambers under guidance of an X-ray machine. In addition to measuring pressures in your heart, cardiac catheterization is used to obtain X-ray images (angiograms) of your heart and blood vessels. A dye is injected through the catheter to help visualize your heart and blood vessels. This test is rarely used to diagnose hypertrophic cardiomyopathy.
Family screening If you have a first-degree relative — parent, sibling or child — with hypertrophic cardiomyopathy, doctors may recommend that you be screened for the condition. Doctors will discuss with you the test results, and the risks and benefits of genetics tests. There are two types of screening:
- Genetic testing. Genetic tests may not provide a definitive answer because the genetic causes of hypertrophic cardiomyopathy aren’t fully understood. Only 50 to 60 percent of families with HCM have a currently detectable mutation, and some insurance companies may not cover genetic testing. However, if an abnormal gene is detected in your family, then other family members can learn if they are at risk of hypertrophic cardiomyopathy through genetic testing. Consultation with a genetic counselor is recommended to help you determine whether genetic testing is a good option for you.
- If genetic testing is not done, or if the results are not helpful, then your doctor may recommend echocardiography on a regular basis if you have a family member with hypertrophic cardiomyopathy. Adolescents and competitive athletes should be screened once a year. Adults who don’t compete in athletics should be screened every five years.
How is hypertrophic cardiomyopathy treated?
The goal of treatment is to relieve symptoms and prevent sudden cardiac death in people at high risk. Specific treatment varies depending on the severity of your symptoms. Your doctor will discuss with you the most appropriate treatment for your condition.
The options include:
- You may be given medications to relax the heart muscle and to slow the heart rate so that the heart can pump more efficiently. Your doctor may recommend beta blockers such as metoprolol (Lopressor, Toprol), propranolol (Inderal, Innopran XL) or atenolol (Tenormin), calcium channel blockers such as verapamil (Verelan, Calan, Covera-HS) or diltiazem (Cardizem, Tiazac, Dilacor XR), or medications to control your heart rhythm such as amiodarone (Cordarone, Pacerone) or disopyramide (Norpace). If you have atrial fibrillation, your doctor may prescribe blood thinners such as warfarin (Coumadin, Jantoven), dabigatran (Pradaxa), rivaroxaban (Xarelto) or apixaban (Eliquis) to reduce your risk of blood clots.
- Septal myectomy. A septal myectomy is an open-heart procedure in which the surgeon removes part of the thickened, overgrown septum between the ventricles. Removing part of this overgrown muscle improves blood flow and reduces mitral regurgitation. Surgeons may conduct this procedure using different approaches, depending on the location of the thickened heart muscle. Surgeons may sometimes perform mitral valve repair at the same time as a myectomy. A myectomy may be recommended if medications don’t relieve your symptoms. Most people who have a myectomy have no further symptoms. Septal myectomy is available only in medical centers that specialize in the treatment of hypertrophic cardiomyopathy.
- Septal ablation. In septal ablation, a small portion of the thickened heart muscle is destroyed by injecting alcohol through a long, thin tube (catheter) into the artery supplying blood to that area. This procedure may improve your symptoms. Possible complications with this procedure include heart block — a disruption of the heart’s electrical system — which requires implantation of a pacemaker.
- Implantable cardioverter-defibrillator (ICD). Doctors may recommend an ICD if you have life-threatening heart rhythm disorders (arrhythmias) such as ventricular tachycardia or ventricular fibrillation. An ICD is a small device that continuously monitors your heartbeat. It’s implanted in your chest like a pacemaker. If a life-threatening arrhythmia occurs, the ICD delivers precisely calibrated electrical shocks to restore a normal heart rhythm. Your doctor may recommend an ICD if you have hypertrophic cardiomyopathy and you’re at high risk of sudden cardiac death because of abnormal heart rhythms.
Lifestyle changes & Home remedies
What are some lifestyle changes or home remedies that can help me manage hypertrophic cardiomyopathy?
The following lifestyles and home remedies might help you cope with hypertrophic cardiomyopathy :
- Physical activity level. Competitive sports are generally not recommended for people with hypertrophic cardiomyopathy. Many people with hypertrophic cardiomyopathy may be able to participate in low- to moderate-intensity exercise as part of a healthy lifestyle. Ask your doctor for guidance.
- Eat a healthy diet. A healthy diet is an important part of maintaining your heart health.
- Maintain a healthy weight. Maintaining a healthy weight will prevent excessive stress on your heart and reduce health risks associated with surgery or other procedures.
- Alcohol use. If you have symptoms or a history of rhythms provoked by alcohol, ask your doctor for guidance about safe levels of alcohol use. Drinking too much alcohol can trigger irregular heart rhythms and can lead to increased blockage of blood flow in your heart.
- Take your medications. Make sure to take your medications as prescribed.
- Have regular medical appointments. Your doctor may recommend regular follow-up appointments to evaluate your condition. Let your doctor know if you have any new or worse symptoms.
Women who have hypertrophic cardiomyopathy can generally have normal pregnancies. However, if you have symptoms and complications of hypertrophic cardiomyopathy, your doctor may recommend that you see a doctor experienced in caring for women with high-risk conditions during your pregnancy.
If you have any questions, please consult with your doctor to better understand the best solution for you.
Hello Health Group does not provide medical advice, diagnosis or treatment.
- Hypertrophic cardiomyopathy. http://www.mayoclinic.org/diseases-conditions/hypertrophic-cardiomyopathy/home/ovc-20122102. Accessed 15 Jan 2017
- hypertrophic cardiomyopathy . http://www.heart.org/HEARTORG/Conditions/More/Cardiomyopathy/Hypertrophic-Cardiomyopathy_UCM_444317_Article.jsp#.WHuNsBt97IU. Accessed 15 Jan 2017
Review Date: June 19, 2017 | Last Modified: June 19, 2017