Exhaled Nitric Oxide Test



What is Exhaled Nitric Oxide Test?

An exhaled nitric oxide level test can help diagnose and manage asthma. It measures the amount of nitric oxide that is exhaled from a breath. Increased levels of nitric oxide are associated with swelling of lung airways. This test can be used to determine whether someone being treated for asthma is responding well to certain medications.

Why is Exhaled Nitric Oxide Test performed?

The diagnosis of asthma is usually made using your medical history, a physical exam, and certain tests to see how well your lungs are working, such as peak flow measurement and spirometry tests. You may need tests that trigger and then treat mild asthma symptoms. These tests are called challenge tests.

Even after these tests, the diagnosis of asthma may still be uncertain, or there may be questions about the best treatment. In these cases the exhaled nitric oxide test may be helpful. Nitric oxide is produced throughout the body, including in the lungs, to fight inflammation and relax tight muscles. High levels of exhaled nitric oxide in your breath can mean that your airways are inflamed — one sign of asthma.

Nitric oxide testing is also done to help predict whether or not steroid medications, which decrease inflammation, are likely to be helpful for your asthma. If you’ve already been diagnosed with asthma and treated with one of the steroid medications, your doctor may use an exhaled nitric oxide test during office visits to help determine whether your asthma is under control.

Exhaled nitric oxide testing may not be necessary or provide useful information for everyone who has asthma. In addition, it may not be available in all hospitals or doctor’s offices.


What should I know before receiving Exhaled Nitric Oxide Test?

This test is quick and very safe. Rarely, some people might feel a little lightheaded when they are asked to breathe out and breathe in. In this case, the technician will ask you to sit and relax for a few minutes, and if you wish, try the test again.


How to prepare for Exhaled Nitric Oxide Test?

Check ahead of time to see whether nitric oxide testing is covered by your insurance. To make sure test results are accurate, you will need to avoid eating and drinking for at least an hour before you take the test.

You will also need to avoid the following for about 24 hours before you take the test:

  • Exercise
  • Alcohol
  • Tobacco
  • Allergy shots

What happens during Exhaled Nitric Oxide Test?

To do this test, you’ll be seated. Your doctor will have you put in a mouthpiece attached to a tube that leads to an electronic measurement device. Next, you’ll breathe in for two or three seconds until your lungs are filled with air. Your doctor will then have you exhale steadily so that the air flows out of your lungs at a steady rate. Your doctor may have you watch a computer monitor that registers how much you’re breathing out so that you can maintain a steady exhalation. The entire test generally takes five minutes or less.

What happens after Exhaled Nitric Oxide Test?

This test doesn’t require any special aftercare. After the test, you can resume your daily routine unless instructed otherwise by your doctor.

If you have any questions about the Exhaled Nitric Oxide Test, please consult with your doctor to better understand your instructions.

Explanation of results

What do my results mean?

Higher than normal levels of exhaled nitric oxide generally mean your airways are inflamed — a sign of asthma.

Levels under about 20 parts per billion in children and under about 25 parts per billion in adults are considered normal.

More than 35 parts per billion in children and 50 parts per billion in adults may signal airway inflammation caused by asthma.

Nitric oxide test results can vary widely from person to person. When interpreting test results, your doctor will consider a number of other factors. These may include:

  • Your asthma signs and symptoms
  • Past nitric oxide test results
  • Results of other tests, such as peak flow tests or spirometry tests
  • Medications you take
  • Whether you have a cold or the flu
  • Whether you have hay fever or other allergies
  • Whether or not you smoke
  • Your age

Depending on the laboratory and hospital, the normal range for Exhaled Nitric Oxide Test may vary. Please discuss with your doctor any questions you may have about your test results.


Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: November 7, 2018 | Last Modified: November 7, 2018

You might also like