Definition

What is Banti’s Syndrome?

The spleen is the large, gland-like organ in the upper left side of the abdomen which produces red blood cells before birth, removes and destroys aged red blood cells in newborns, and plays a vital role in fighting infection. Banti’s syndrome is a chronic congestive enlargement of the spleen which leads to premature destruction of the red blood cells by the spleen. It is named after the Italian pathologist and physician Guido Banti.

How common is Banti’s Syndrome?

Banti’s Syndrome is a rare condition. It affects males and females equally. It is relatively common in parts of India and Japan, but rare in Western countries. Increased arsenic levels are present in drinking water in some countries and may contribute to regional differences in incidence. Please discuss with your doctor for further information.

Symptoms

What are the symptoms of Banti’s Syndrome?

The common symptoms of Banti’s Syndrome are:

  • Blood in vomit
  • Melena
  • Weakness
  • Flatulence
  • Diarrhea
  • Abdominal pain
  • Abdominal distress
  • Vague indigestion
  • Abdominal pain
  • Abdominal distress
  • Nosebleed
  • Pallor
  • Mild jaundice
  • Brown skin pigmentation
  • Sallow skin
  • Enlarged liver
  • Enlarged spleen
  • Anemia
  • Flapping hand tremor
  • Muscle wasting
  • Ascites
  • Swelling
  • Leukopenia
  • Cirrhosis of the liver
  • Increased portal vein hypertension

There may be some symptoms not listed above. If you have any concerns about a symptom, please consult your doctor.

When should I see my doctor?

If you have any signs or symptoms listed above or have any questions, please consult with your doctor. Everyone’s body acts differently. It is always best to discuss with your doctor what is best for your situation.

Causes

What causes Banti’s Syndrome?

Banti syndrome may occur due to a number of different factors causing obstruction of, and abnormally increased blood pressure (hypertension) within, certain veins of the spleen (splenic veins) or the liver (e.g., hepatic or portal veins). These may include abnormalities present at birth (congenital) of such veins, blood clots, or various underlying disorders causing inflammation and obstruction of veins (vascular obstruction) of the liver, such as cirrhosis. Increased arsenic intake has also been implicated in some cases. Also, cases have occurred in patients taking long-term azathioprine, particularly after kidney transplantation.

Risk factors

What increases my risk for Banti’s Syndrome?

Please discuss with your doctor for further information.

Diagnosis & treatment

The information provided is not a substitute for any medical advice. ALWAYS consult with your doctor for more information.

How is Banti’s Syndrome diagnosed?

The diagnosis of Banti’s syndrome my be confirmed by a thorough clinical evaluation and a variety of specialized tests, particularly advanced imaging techniques such as a splenic venography and magnetic resonance imaging (MRI).

How is Banti’s Syndrome treated?

The treatment of Banti’s syndrome depends upon its cause. In cases where Banti’s syndrome is caused by azathioprine or arsenic, the patient’s exposure to these factors would need to be stopped immediately. The main issues in Banti’s syndrome are bleeding from esophagus and varices, i.e. dilated gastric blood vessels. Active bleeding in Banti’s syndrome can be treated effectively with vasoconstrictor drugs or through other methods used to treat portal hypertension. In case of recurrent bleeding in Banti’s syndrome, the doctor may choose to reroute the blood flow with a surgical shunt.

Lifestyle changes & home remedies

What are some lifestyle changes or home remedies that can help me manage Banti’s Syndrome?

If you have any questions, please consult with your doctor to better understand the best solution for you.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: May 22, 2018 | Last Modified: May 22, 2018

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